Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 14/20 | 0.40 |
| ▸ | PPARA | Q07869 | 10/20 | 0.40 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536372 | 0.88 | PPARD (0.45) | CNR1PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3539259 | 0.80 | PPARD (0.42) | CNR1PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3542725 | 0.79 | PPARD (0.45) | CNR1PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3537640 | 0.77 | PPARD (0.44) | CNR1PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3537011 | 0.73 | CYP11B1 (0.41) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3533934 | 0.73 | PPARD (0.39) | CNR1PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3764067 | 0.72 | CDK1 (0.42) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL15160329 | 0.71 | PPARD (0.61) | PPARDPPARAPPARGFFAR1MAPT | |
| SCHEMBL18003806 | 0.71 | MAPT (0.52) | PPARDPPARAPPARGFFAR1MAPT | |
| SCHEMBL3745525 | 0.70 | XDH (0.41) | PPARDPPARAPPARGAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709509-B2 | Oxadiazolones and derivatives thereof as peroxisome proliferator-activated receptor (PPAR) delta agonists | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-05-04 | — | — | US | disclosed |