SCHEMBL3540335

SCHEMBL3540335

CCOC(Cc1ccc(S)cc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 20/20 0.66
PPARG P37231 11/20 0.58
PPARD Q03181 13/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5543269 0.85 PPARA (0.72) PPARAPPARGPPARD
SCHEMBL543815 0.85 PPARA (0.72) PPARAPPARGPPARD
SCHEMBL17680422 0.85 PPARA (0.68) PPARAPPARGPPARD
SCHEMBL3233074 0.85 PPARA (0.72) PPARAPPARGPPARD
SCHEMBL4993002 0.84 PPARA (0.69) PPARAPPARGPPARD
SCHEMBL1670312 0.84 PPARA (0.69) PPARAPPARGPPARD
SCHEMBL3536105 0.84 PPARA (0.48) PPARAPPARGPPARD
SCHEMBL24328379 0.83 PPARA (0.66) PPARAPPARGPPARD
SCHEMBL4074678 0.83 PPARA (0.66) PPARAPPARGPPARD
SCHEMBL756057 0.83 PPARA (0.66) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816385-B2 Dimeric dicarboxylic acid derivatives, their preparation and use HIGH POINT PHARMACEUTICALS, LLC (US) 2010-10-19 US disclosed
EP-1578716-A1 DICARBOXYLIC ACID DERIVATIVES AS PPAR-AGONISTS NOVO NORDISK A/S (DK) 2005-09-28 EP disclosed
US-20040259950-A1 Novel compounds, their preparation and use HIGH POINT PHARMACEUTICALS, LLC 2004-12-23 US disclosed
WO-2004056740-A1 DICARBOXYLIC ACID DERIVATIVES AS PPAR-AGONISTS NOVO NORDISK A/S (DK) 2004-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040259950-A1 Novel compounds, their preparation and use PPARG, PPARA, PPARD PPARA 2/4885PPARG 1/4885PPARD 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.