⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21484044 | 1.00 | ALDH1A1 (0.31) | — | |
| SCHEMBL21484043 | 1.00 | ALDH1A1 (0.31) | — | |
| SCHEMBL354036 | 1.00 | — | — | |
| SCHEMBL28731012 | 0.86 | — | — | |
| SCHEMBL8568126 | 0.83 | TSHR (0.37) | — | |
| SCHEMBL1114100 | 0.83 | — | — | |
| SCHEMBL8568123 | 0.83 | TSHR (0.37) | — | |
| SCHEMBL1114099 | 0.83 | — | — | |
| SCHEMBL8568120 | 0.83 | TSHR (0.37) | — | |
| SCHEMBL28978872 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430538-A | Thioester cationic lipids | 川斯勒佰尔公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-115768399-A | Process for dyeing keratin materials comprising the use of an organosilicon compound, an alkyl (poly) glycoside, a colorant compound and a post-treatment agent | 汉高股份有限及两合公司 | 2023-03-07 | — | — | CN | disclosed |
| US-20220016082-A1 | COMBINATION THERAPIES FOR HIGH AND VERY HIGH RISK MDS | MEI PHARMA, INC. | 2022-01-20 | — | — | US | disclosed |
| EP-3886865-A1 | COMBINATION THERAPIES FOR HIGH AND VERY HIGH RISK MDS | MEI Pharma, Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| US-20210100775-A1 | COMBINATION THERAPIES | MEI PHARMA, INC. | 2021-04-08 | — | — | US | disclosed |
| EP-3662911-A1 | COMBINATION OF AZACITIDINE AND PRACINOSTAT TO TREAT MYELODYSPLASTIC SYNDROME (MDS) | MEI Pharma, Inc. (US) | 2020-06-10 | — | — | EP | disclosed |
| WO-2020112848-A1 | COMBINATION THERAPIES FOR HIGH AND VERY HIGH RISK MDS | MEI PHARMA, INC. (US) | 2020-06-04 | — | — | WO | disclosed |
| EP-2914254-B1 | COMBINATION THERAPIES TO TREAT CHEMORESISTANT CANCERS | MEI PHARMA INC (US) | 2020-01-08 | — | — | EP | disclosed |
| CN-107074757-B | The manufacturing method of trifluoromethyl alkylthio chemical combination object | 组合化学工业株式会社 | 2019-05-03 | — | — | CN | disclosed |
| EP-2131840-B1 | COMBINATION OF BENZIMIDAZOLE ANTI-CANCER AGENT AND A SECOND ANTI-CANCER AGENT | MEI PHARMA INC (US) | 2018-10-17 | — | — | EP | disclosed |
| US-6683183-B2 | BICYCLIC HETEROCYCLES THAT INHIBIT CYCLIN-DEPENDENT KINASE OR TYROSINE KINASE ENZYMES, OR BOTH, FOR TREATMENT OF PROLIFERATIVE DISORDERS | WARNER-LAMBERT COMPANY | 2004-01-27 | — | — | US | disclosed |
| US-20030113533-A1 | Double sided adhesive tape | TESA SE (DE) | 2003-06-19 | — | — | US | disclosed |
| US-20020061865-A1 | Pyridotriazines and pyridopyridazines | KRAMER JAMES BERNARD (US) | 2002-05-23 | — | — | US | disclosed |
| EP-1195378-A1 | Pyridotriazines and pyridopyridazines | WARNER-LAMBERT COMPANY (US) | 2002-04-10 | — | — | EP | disclosed |
| EP-1080092-A2 | BICYCLIC PYRIMIDINES AND BICYCLIC 3,4-DIHYDROPYRIMIDINES AS INHIBITORS OF CELLULAR PROLIFERATION | WARNER-LAMBERT COMPANY (US) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999061444-A2 | BICYCLIC PYRIMIDINES AND BICYCLIC 3,4-DIHYDROPYRIMIDINES AS INHIBITORS OF CELLULAR PROLIFERATION | WARNER-LAMBERT COMPANY (US) | 1999-12-02 | — | — | WO | disclosed |
| WO-1997026873-A1 | ANTIMICROBIAL AURONE DERIVATIVES | PHYTERA, INC. (US) | 1997-07-31 | — | — | WO | disclosed |
| US-5597854-A | PHOTOGRAPHIC APPLICATIONS, COATINGS, BINDERS, POLYMERS, TRIAZINE OR PYRIMIDINE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1997-01-28 | — | — | US | disclosed |
| EP-0039913-B1 | TETRAZOLYLCOUMARIN DERIVATIVES, PROCESS FOR PREPARING THE SAME AND COMPOSITION CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1985-01-23 | — | — | EP | disclosed |
| EP-0021637-A1 | Amidothiol derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1981-01-07 | — | — | EP | disclosed |