SCHEMBL354233

SCHEMBL354233

Cc1ccc2ncoc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.49
KDM4E B2RXH2 5/20 0.44
MAPT P10636 3/20 0.44
LMNA P02545 1/20 0.44
NQO2 P16083 1/20 0.43
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
HSD17B10 Q99714 2/20 0.42
PRKD1 Q15139 1/20 0.41
ALDH1A1 P00352 4/20 0.41
HPGD P15428 2/20 0.41
TP53 P04637 1/20 0.41
PKM P14618 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL27569854 0.96 DYRK1A (0.50) DYRK1AKDM4EMAPTLMNANQO2
SCHEMBL11305559 0.91 DYRK1A (0.42) DYRK1AKDM4EMAPTLMNANQO2
SCHEMBL10526428 0.89 DYRK1A (0.41) DYRK1AKDM4EMAPTLMNANQO2
SCHEMBL423908 0.83 DYRK1A (0.49) DYRK1AKDM4EMAPTNQO2NPC1
SCHEMBL29687792 0.83 DYRK1A (0.49) DYRK1AKDM4EMAPTNQO2NPC1
SCHEMBL9298986 0.80 CTNNB1 (0.52) KDM4EMAPTNPC1RAB9ASMN1; SMN2
Ethylene SCHEMBL18420722 0.79 DYRK1A (0.46) DYRK1AKDM4EMAPTNQO2NPC1
Benzene SCHEMBL152659 0.79 CTNNB1 (0.51) DYRK1AKDM4ENQO2NPC1RAB9A
Benzo[D]Oxazole SCHEMBL10438872 0.79 NQO2 (0.50) DYRK1AKDM4ENQO2NPC1RAB9A
SCHEMBL24425916 0.77 DYRK1A (0.72) DYRK1ALMNANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058630-A Triaryl substituted vinyl compound and synthesis method thereof 海南大学 2025-05-30 CN claimed
CN-117926287-A Method for synthesizing 2-aminobenzoxazole derivative under electrochemical condition 湘潭大学 2024-04-26 CN claimed
US-20190071416-A1 COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-03-07 US claimed
EP-3371151-A1 COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS Agency For Science, Technology And Research (SG) 2018-09-12 EP claimed
WO-2017061957-A1 COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-04-13 WO claimed
EP-2091929-A1 AGENTS THAT DISRUPT CELLULAR REPLICATION AND THEIR USE IN INHIBITING PATHOLOGICAL CONDITIONS The European Molecular Biology Laboratory (DE) 2009-08-26 EP claimed
CN-101421257-A Agents that disrupt cellular replication and their use in inhibiting pathological conditions EUROPEAN MOLECULAR BIOLOGY LAB EMBL (DE) 2009-04-29 CN claimed
WO-2007107352-A1 AGENTS THAT DISRUPT CELLULAR REPLICATION AND THEIR USE IN INHIBITING PATHOLOGICAL CONDITIONS THE EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) 2007-09-27 WO claimed
EP-0278509-B1 Silver halide photographic emulsion FUJI PHOTO FILM CO LTD (JP) 1996-01-24 EP claimed
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
US-4970141-A ELEVATED SPECTRAL SENSITIVITY IN GREEN WAVELENGTH REGION FUJI PHOTO FILM CO., LTD. (JP) 1990-11-13 US claimed
US-4891305-A LASERS RICOH CO., LTD. (JP) 1990-01-02 US claimed
US-4889796-A CONTAINING BENZOXAZOLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1989-12-26 US claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
US-4772534-A PHOTORESISTS FUJI PHOTO FILM CO., LTD. (JP) 1988-09-20 US claimed
EP-0278509-A2 Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1988-08-17 EP claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-4154616-A BENZOXAZOLE OR NAPHTHOXAZOLE MEROCYANINE DYE FUJI PHOTO FILM CO., LTD. (JP) 1979-05-15 US claimed
US-4057430-A MEROCYANINE THIOHYDANTOIN SENSITIZERS FUJI PHOTO FILM CO., LTD. (JA) 1977-11-08 US claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190071416-A1 COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS SMYD3, SMYD2, EHMT1 DYRK1A 3452/4885KDM4E 54/4885MAPT 4633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.