SCHEMBL354332

SCHEMBL354332

NCc1ccc([N+](=O)[O-])cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 1.00
IDO1 P14902 4/20 0.61
TSHR P16473 1/20 0.57
ALDH1A1 P00352 2/20 0.56
CYP2C19 P33261 3/20 0.53
POLB P06746 1/20 0.53
CA9 Q16790 3/20 0.50
CYP1A2 P05177 2/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA14 Q9ULX7 2/20 0.50
ACHE P22303 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CYP2C9 P11712 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL31513716 0.98 LOXL2 (0.95) LOXL2IDO1TSHRALDH1A1CYP2C19
Methane SCHEMBL11552193 0.98 LOXL2 (0.95) LOXL2IDO1TSHRALDH1A1CYP2C19
Hydrochloric Acid SCHEMBL726 0.98 LOXL2 (0.95) LOXL2IDO1TSHRALDH1A1CYP2C19
Hydrochloric Acid SCHEMBL28059156 0.96 LOXL2 (0.91) LOXL2IDO1TSHRALDH1A1CYP2C19
Methane SCHEMBL29190749 0.96 LOXL2 (0.91) LOXL2IDO1TSHRALDH1A1CYP2C19
SCHEMBL4687550 0.94 LOXL2 (0.88) LOXL2IDO1TSHRALDH1A1CYP2C19
Phosphonic Acid SCHEMBL27895241 0.90 LOXL2 (0.81) LOXL2IDO1TSHRALDH1A1CYP2C19
SCHEMBL11816242 0.90 LOXL2 (0.81) LOXL2IDO1TSHRALDH1A1CYP2C19
Benzylamine SCHEMBL27935312 0.89 LOXL2 (0.80) LOXL2IDO1ALDH1A1CYP2C19CYP1A2
SCHEMBL12635614 0.88 LOXL2 (0.78) LOXL2IDO1TSHRALDH1A1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2162 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977906-A A-site cation-regulated halide perovskite, and preparation method and application thereof 西北大学 2025-05-13 CN claimed
CN-119633898-A Preparation method and application of donor-acceptor type two-dimensional imino CTF photocatalyst 天津理工大学 2025-03-18 CN claimed
CN-115286527-B Preparation method and application of nopic acid amide compounds 南京林业大学 2024-09-13 CN claimed
CN-118546097-A 4, 6-Diaryl-2-substituted pyrimidine guanidine compound and preparation method and application thereof 云南大学 2024-08-27 CN claimed
CN-118324707-A Synthesis method of (S) -6-hydroxymethyl-morpholin-3-one 西安宇特邦医药科技有限公司 2024-07-12 CN claimed
CN-117510429-A Compound containing methyl isoxazole structure, and preparation method and application thereof 中国农业大学 2024-02-06 CN claimed
CN-114874153-B Synthetic method of naphtho [2,1-d ] oxazole compound 湖南第一师范学院 2023-11-17 CN claimed
CN-114957152-B Synthesis method of benzoxazole compound 湖南第一师范学院 2023-11-17 CN claimed
CN-112795377-B Preparation and application technical field of novel fluorescent probe with ICT-PET effect and capable of being used for formaldehyde detection 湖南超亟检测技术有限责任公司 2022-12-09 CN claimed
CN-115286527-A Preparation method and application of nopyl acid amide compounds 南京林业大学 2022-11-04 CN claimed
US-5767238-A Inverse solid phase synthesis COMBICHEM, INC. (US) 1998-06-16 US claimed
US-5639742-A ANTIBIOTIC; BACTERICIDE LEE VING JICK (US) 1997-06-17 US claimed
WO-1997016428-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1997-05-09 WO claimed
US-5371076-A ANTIBIOTICS AMERICAN CYANAMID COMPANY (US) 1994-12-06 US claimed
EP-0618190-A1 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines AMERICAN CYANAMID COMPANY (US) 1994-10-05 EP claimed
US-5254679-A Containing a quaternized nitrogen IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-10-19 US claimed
WO-1992006081-A1 ANILIDE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST PROPERTIES WARNER-LAMBERT COMPANY (US) 1992-04-16 WO claimed
US-5049558-A Quaternized nitrogen-heterocycle substituted IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-09-17 US claimed
EP-0164944-B1 CEPHALOSPORIN DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-07-11 EP claimed
EP-0164944-A1 Cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-18 EP claimed