⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10250082 | 1.00 | — | — | |
| SCHEMBL11305817 | 1.00 | — | — | |
| SCHEMBL11385889 | 0.81 | ALDH1A1 (0.35) | — | |
| SCHEMBL1785110 | 0.77 | — | — | |
| SCHEMBL7761713 | 0.77 | TSHR (0.40) | — | |
| SCHEMBL6728883 | 0.77 | — | — | |
| SCHEMBL1785108 | 0.77 | — | — | |
| SCHEMBL6728878 | 0.77 | — | — | |
| SCHEMBL7759825 | 0.77 | TSHR (0.40) | — | |
| SCHEMBL16449145 | 0.77 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114717280-A | Synthesis method of monopilavir | 浙江工业大学 | 2022-07-08 | — | — | CN | claimed |
| CN-116615411-A | Process for producing peptide compound containing N-substituted amino acid residue | 中外制药株式会社 | 2023-08-18 | — | — | CN | disclosed |
| CN-114717280-A | Synthesis method of monopilavir | 浙江工业大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114717280-A | Synthesis method of monopilavir | 浙江工业大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-103739574-B | A kind of synthetic method of 5H-furans-2-ketone compounds of replacement | JIANG University OF TECHNOLOGY (CN) | 2015-08-26 | — | — | CN | disclosed |
| US-20140329746-A1 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2014-11-06 | — | — | US | disclosed |
| US-8835654-B2 | Method and compositions for treating amyloid-related diseases | BHI LIMITED PARTNERSHIP (CA) | 2014-09-16 | — | — | US | disclosed |
| EP-1642934-B1 | TRANSPARENT RESIN COMPOSITION | SANYO CHEMICAL IND LTD (JP) | 2012-12-12 | — | — | EP | disclosed |
| US-20120015911-A1 | METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | BELLUS HEALTH INC. (CA) | 2012-01-19 | — | — | US | disclosed |
| US-8044100-B2 | Methods and compositions for treating amyloid-related diseases | BELLUS HEALTH INC. (CA) | 2011-10-25 | — | — | US | disclosed |
| EP-0007089-B1 | ACYLANILIDES WITH HERBICIDAL AND FUNGICIDAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND THEIR USE | Consortium für elektrochemische Industrie GmbH (DE) | 1981-09-16 | — | — | EP | disclosed |
| US-4264456-A | IN FABRIC SOFTENER | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-04-28 | — | — | US | disclosed |
| US-4259214-A | PERFUME ADDITIVE | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-03-31 | — | — | US | disclosed |
| US-4255275-A | FOR SOLID OR LIQUID DETERGENTS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4241097-A | Use of benzodionones in augmenting or enhancing the aroma and taste of a foodstuff | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1980-12-23 | — | — | US | disclosed |
| EP-0007089-A1 | Acylanilides with herbicidal and fungicidal activity, process for their preparation and their use | Consortium für elektrochemische Industrie GmbH (DE) | 1980-01-23 | — | — | EP | disclosed |
| US-4000327-A | BERRY FRUIT FOODSTUFFS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-12-28 | — | — | US | disclosed |
| US-3984579-A | Novel flavoring compositions and products containing isomer mixtures containing high proportions of 2-methyl-cis-3-pentenoic acid | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-10-05 | — | — | US | disclosed |
| US-3931306-A | Process for producing isomer mixtures containing high proportions of cis-2-methyl-3-pentenoic acid | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-01-06 | — | — | US | disclosed |
| US-3931293-A | Processes for producing cis alkyl-2-methyl-3-pentenoates and isomer mixtures containing high proportions of cis alkyl-2-methyl-3-pentenoates | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-01-06 | — | — | US | disclosed |