SCHEMBL354478

SCHEMBL354478

O=S(=O)(O)CC(Cl)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8172351 0.78
SCHEMBL8172353 0.75
SCHEMBL8746851 0.75 CYP1A2 (0.31)
SCHEMBL17663781 0.75
Hydrochloric Acid SCHEMBL27808030 0.73 CYP1A2 (0.31)
SCHEMBL16445636 0.73
SCHEMBL2291577 0.72 CA5A (0.36)
SCHEMBL2258298 0.72
SCHEMBL5070465 0.71
SCHEMBL11793282 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1537163-B1 METHOD FOR PREPARING WATER-SOLUBLE POLYMER DERIVATIVES BEARING A TERMINAL CARBOXYLIC ACID NEKTAR THERAPEUTICS AL CORP (US) 2008-10-29 EP claimed
JP-2006516295-A 2006-06-29 JP claimed
CN-1744918-A Polymeric reagents comprising a ketone or a related functional group NEKTAR THERAPEUTICS AL CORP (US) 2006-03-08 CN claimed
EP-1581260-A2 POLYMERIC REAGENTS COMPRISING A KETONE OR A RELATED FUNCTIONAL GROUP Nektar Therapeutics Al, Corporation (US) 2005-10-05 EP claimed
EP-1537163-A2 METHOD FOR PREPARING WATER-SOLUBLE POLYMER DERIVATIVES BEARING A TERMINAL CARBOXYLIC ACID Nektar Therapeutics Al, Corporation (US) 2005-06-08 EP claimed
US-20050036978-A1 Hydrolysing water-soluble polyoxyethylene glycol segment having alkoxide ion or thiolate ion with ortho ester comprised of suitable leaving group (methanesulfonate) NEKTAR THERAPEUTICS 2005-02-17 US claimed
WO-2004060406-A2 POLYMERIC REAGENTS COMPRISING A KETONE OR A RELATED FUNCTIONAL GROUP NEKTAR THERAPEUTICS AL, CORPORATION (US) 2004-07-22 WO claimed
WO-2004022629-A2 METHOD FOR PREPARING WATER-SOLUBLE POLYMER DERIVATIVES BEARING A TERMINAL CARBOXYLIC ACID NEKTAR THERAPEUTICS AL, CORPORATION (US) 2004-03-18 WO claimed
US-20250020997-A1 PHOTORESIST COMPOSITIONS AND METHODS OF MANUFACTURING INTEGRATED CIRCUIT DEVICES USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-01-16 US disclosed
EP-3957627-B1 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SHIONOGI & CO (JP) 2024-06-19 EP disclosed
EP-4371979-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT Kumiai Chemical Industry Co., Ltd. (JP) 2024-05-22 EP disclosed
CN-114853797-B Preparation method of alpha-amino boron ring compound 中山大学 2023-07-21 CN disclosed
US-11685740-B2 Bicyclic nitrogen-containing heterocyclic derivatives and pharmaceutical composition comprising the same SHIONOGI & CO., LTD. (JP) 2023-06-27 US disclosed
US-20230176481-A1 FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-06-08 US disclosed
WO-1996037471-A1 N-AMINOPYRIDONE DERIVATIVES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-11-28 WO disclosed
EP-0486937-B1 Hydrazone derivatives, processes for production thereof, and uses thereof NIHON NOHYAKU CO LTD (JP) 1995-03-22 EP disclosed
US-5358965-A Agricultural and horticultural insecticides, activity against moths and beetles NIHON NOHYAKU CO., LTD. (JP) 1994-10-25 US disclosed
US-5304573-A Insecticides NIHON NOHYAKU CO., LTD. (JP) 1994-04-19 US disclosed
EP-0537463-A2 Substituted pyrido(2,3-d)pyrimidines as antidotes BASF Aktiengesellschaft (DE) 1993-04-21 EP disclosed
EP-0486937-A1 Hydrazone derivatives, processes for production thereof, and uses thereof NIHON NOHYAKU CO., LTD. (JP) 1992-05-27 EP disclosed