SCHEMBL35464

SCHEMBL35464

C=C(C)COCC(O)COC(CC)[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12094886 0.85
SCHEMBL268690 0.81
SCHEMBL9001662 0.80
SCHEMBL4895728 0.78
SCHEMBL331750 0.78 TSHR (0.41)
SCHEMBL2770384 0.77 USP2 (0.33)
SCHEMBL9715020 0.76
SCHEMBL4972431 0.74
SCHEMBL201963 0.74 KDM4E (0.34)
SCHEMBL3627739 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
US-20250223392-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC (CH) 2025-07-10 US claimed
US-12286501-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2025-04-29 US claimed
US-20240254269-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2024-08-01 US claimed
US-20240159938-A1 Compositions for Ophthalmologic Devices JOHNSON & JOHNSON VISION CARE, INC. 2024-05-16 US claimed
US-11926689-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2024-03-12 US claimed
US-20220380509-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2022-12-01 US claimed
US-11453736-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2022-09-27 US claimed
US-11360241-B2 Biomedical devices containing internal wetting agents JOHNSON & JOHNSON VISION CARE, INC. (US) 2022-06-14 US claimed
EP-1534759-A1 MACROMER FORMING CATALYSTS Johnson & Johnson Vision Care, Inc. (US) 2005-06-01 EP claimed
WO-2005005517-A2 SILICONE HYDROGELS HAVING CONSISTENT CONCENTRATIONS OF MULTI-FUNCTIONAL POLYSILOXANES JOHNSON & JOHNSON VISION CARE, INC. (US) 2005-01-20 WO claimed
EP-1425052-A2 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS Johnson & Johnson Vision Care, Inc. (US) 2004-06-09 EP claimed
EP-1425053-A2 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS Johnson & Johnson Vision Care, Inc. (US) 2004-06-09 EP claimed
US-20040002556-A1 Macromer forming catalysts JOHNSON & JOHNSON VISION CARE, INC. 2004-01-01 US claimed
WO-2004000888-A1 MACROMER FORMING CATALYSTS JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-12-31 WO claimed
US-20030162862-A1 Contact lenses for extended wear (without surface treatment, coating-free), formed by reacting polyvinylpyrrolidone and (2-methacryloxy-3-hydroxypropyloxy)propylbis(trimethylsiloxy) methylsilane, then curing JOHNSON & JOHNSON VISION CARE, INC. 2003-08-28 US claimed
US-20030125498-A1 Biomedical devices containing internal wetting agents JOHNSON & JOHNSON VISION CARE, INC. 2003-07-03 US claimed
WO-2003022321-A2 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-03-20 WO claimed
WO-2003022322-A2 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-03-20 WO claimed