SCHEMBL3548009

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3540577	0.88	NPY5R (0.41)	PIK3C3NPY5RKDM4EALDH1A1PDE10A
	SCHEMBL3545469	0.86	PDK2 (0.46)	PIK3C3NPY5RCYP1A2KDM4EALDH1A1
	SCHEMBL3544442	0.85	PDK2 (0.43)	PIK3C3NPY5RCYP1A2KDM4EALDH1A1
	SCHEMBL3544038	0.83	PIK3C3 (0.46)	PIK3C3NPY5RCYP1A2ALDH1A1PDE10A
	SCHEMBL14313951	0.82	P2RX7 (0.42)	PIK3C3NPY5RPDE10AFFAR1P2RX7
	SCHEMBL824620	0.81	AR (0.48)	PIK3C3NPY5RKDM4EALDH1A1PDE10A
	SCHEMBL824626	0.81	AR (0.51)	PIK3C3NPY5RPDE10AJAK2JAK1
	SCHEMBL3542628	0.81	PIK3C3 (0.40)	PIK3C3NPY5RKDM4EALDH1A1PDE10A
	SCHEMBL3545025	0.81	TNKS (0.44)	PIK3C3NPY5RCYP1A2KDM4EALDH1A1
	SCHEMBL824897	0.80	AR (0.50)	PIK3C3NPY5RPDE10AJAK2JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.