Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | ACACB | O00763 | 7/20 | 0.39 |
| ▸ | CASR | P41180 | 5/20 | 0.37 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3549591 | 0.89 | ACACB (0.44) | NOTUMACACBCASRSMPD3 | |
| SCHEMBL3548678 | 0.81 | ACACB (0.38) | ACACB | |
| SCHEMBL3554678 | 0.77 | MAPK1 (0.43) | NOTUM | |
| SCHEMBL1969010 | 0.75 | MTNR1A (0.67) | NOTUMMTNR1AMTNR1BCASRSMPD3 | |
| SCHEMBL1969011 | 0.75 | MTNR1A (0.67) | NOTUMMTNR1AMTNR1BCASRSMPD3 | |
| SCHEMBL19702029 | 0.72 | NOTUM (0.64) | NOTUMMTNR1AMTNR1BACACBSMPD3 | |
| SCHEMBL1969230 | 0.68 | MTNR1A (0.69) | NOTUMMTNR1AMTNR1B | |
| SCHEMBL3552127 | 0.68 | MCHR1 (0.47) | NOTUMACACB | |
| SCHEMBL1965717 | 0.68 | MTNR1A (0.69) | NOTUMMTNR1AMTNR1B | |
| SCHEMBL23387210 | 0.67 | NOTUM (0.67) | NOTUMMTNR1AMTNR1BACACBCASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718801-B2 | Substituted imidazole derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-05-18 | — | — | US | disclosed |
| US-20080070894-A1 | Novel Substituted Imidazole Derivative | MSD K.K. (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-1790650-A1 | NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070894-A1 | Novel Substituted Imidazole Derivative | PLK1, CDK1, CDK11A | NOTUM 3299/4885MTNR1A 1849/4885MTNR1B 2170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.