Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.75 |
| ▸ | RXRB | P28702 | 3/20 | 0.75 |
| ▸ | RXRG | P48443 | 3/20 | 0.75 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22555982 | 0.87 | RXRA (0.61) | RXRARXRBRXRGMRGPRX4PTGER1 | |
| SCHEMBL1600077 | 0.87 | MRGPRX4 (0.62) | RXRARXRBRXRGMRGPRX4PTGER1 | |
| SCHEMBL29556736 | 0.87 | MRGPRX4 (0.62) | RXRARXRBRXRGMRGPRX4PTGER1 | |
| Hydrochloric Acid SCHEMBL10857748 | 0.85 | MRGPRX4 (0.61) | RXRARXRBRXRGMRGPRX4PTGER1 | |
| SCHEMBL2802191 | 0.83 | RXRA (0.55) | RXRARXRBRXRGMRGPRX4PTGER1 | |
| SCHEMBL6208609 | 0.82 | RXRA (0.57) | RXRARXRBRXRGMRGPRX4NPC1 | |
| SCHEMBL3367612 | 0.82 | RXRA (0.54) | RXRARXRBRXRGMRGPRX4RAB9A | |
| SCHEMBL79709 | 0.82 | RXRA (0.72) | RXRARXRBRXRGMRGPRX4PTGER1 | |
| SCHEMBL849231 | 0.82 | RXRA (0.72) | RXRARXRBRXRGMRGPRX4PTGER1 | |
| SCHEMBL27051627 | 0.82 | RXRA (0.57) | RXRARXRBRXRGMRGPRX4PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691843-B2 | N-hydroxyamide derivatives possessing antibacterial activity | PFIZER INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20080058304-A1 | N-hydroxyamide derivatives possessing antibacterial activity | VICURON HOLDINGS LLC | 2008-03-06 | — | — | US | disclosed |
| EP-1539744-A4 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARM INC (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1539744-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004007444-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058304-A1 | N-hydroxyamide derivatives possessing antibacterial activity | AMDHD2, OGA, ENGASE | RXRA 4524/4885RXRB 4684/4885RXRG 4640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.