Bli-489

Bli-489

SCHEMBL3549034

O=C(O)C1=CS[C@@H]2/C(=C\c3cn4c(n3)COCC4)C(=O)N12

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bli-489 SCHEMBL2930081 1.00
Bli-489 SCHEMBL2930077 1.00
Bli-489 SCHEMBL5370434 0.99
Bli-489 SCHEMBL5370425 0.99
SCHEMBL13959069 0.93
Bli-489 SCHEMBL5370432 0.90
SCHEMBL3217524 0.85
SCHEMBL2929074 0.85
SCHEMBL2929072 0.85
SCHEMBL3553666 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475441-B1 METHODS, SYSTEMS AND/OR KITS FOR DETECTING ANTIMICROBIAL RESISTANCE IN BACTERIA BECTON DICKINSON CO (US) 2026-03-25 EP claimed
US-20250290116-A1 COMPOSITIONS, METHODS, SYSTEMS AND/OR KITS FOR DETECTING ANTIMICROBIAL RESISTANCE IN BACTERIA BECTON DICKINSON CO (US) 2025-09-18 US claimed
US-12234499-B2 Compositions, methods, systems and/or kits for detecting antimicrobial resistance in bacteria BECTON, DICKINSON AND COMPANY (US) 2025-02-25 US claimed
CN-116855575-A Compositions, methods, systems and/or kits for detecting antimicrobial resistance in bacteria 贝克顿迪金森公司 2023-10-10 CN claimed
CN-109642249-B Compositions, methods, systems and/or kits for detecting antimicrobial resistance in bacteria 贝克顿迪金森公司 2023-07-18 CN claimed
US-20220380830-A1 COMPOSITIONS, METHODS, SYSTEMS AND/OR KITS FOR DETECTING ANTIMICROBIAL RESISTANCE IN BACTERIA BECTON DICKINSON CO (US) 2022-12-01 US claimed
CN-114315863-A Preparation method of faropenem sodium 赤峰万泽药业股份有限公司 2022-04-12 CN claimed
US-11286512-B2 Compositions, methods, systems and/or kits for detecting antimicrobial resistance in bacteria BECTON, DICKINSON AND COMPANY (US) 2022-03-29 US claimed
US-20070129344-A1 Bicyclic 6-alkylidene-penem beta-lactamase inhibitors and beta-lactam antibiotic combination: a broad spectrum antibiotic WYETH (US) 2007-06-07 US claimed
US-20060217361-A1 Bicyclic 6-alkylidene-penems as beta-lactamase inhibitors WYETH (US) 2006-09-28 US claimed
US-7112582-B2 Bicyclic 6-alkylidene-penems as β-lactamase inhibitors WYETH (US) 2006-09-26 US claimed
EP-3475441-B1 METHODS, SYSTEMS AND/OR KITS FOR DETECTING ANTIMICROBIAL RESISTANCE IN BACTERIA BECTON DICKINSON CO (US) 2026-03-25 EP disclosed
US-20250290116-A1 COMPOSITIONS, METHODS, SYSTEMS AND/OR KITS FOR DETECTING ANTIMICROBIAL RESISTANCE IN BACTERIA BECTON DICKINSON CO (US) 2025-09-18 US disclosed
US-12234499-B2 Compositions, methods, systems and/or kits for detecting antimicrobial resistance in bacteria BECTON, DICKINSON AND COMPANY (US) 2025-02-25 US disclosed
US-11980631-B2 β-lactamase inhibitors OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2024-05-14 US disclosed
US-20060276445-A1 Bicyclic 6-alkylidene-penems as class-D beta-lactamases inhibitors WYETH (US) 2006-12-07 US disclosed
US-20060217361-A1 Bicyclic 6-alkylidene-penems as beta-lactamase inhibitors WYETH (US) 2006-09-28 US disclosed
US-7112582-B2 Bicyclic 6-alkylidene-penems as β-lactamase inhibitors WYETH (US) 2006-09-26 US disclosed
US-20040132708-A1 Process for preparing 6-alkylidene penem derivatives WYETH 2004-07-08 US disclosed
US-20040053913-A1 Process for preparing 6-alkylidene penem derivatives WYETH 2004-03-18 US disclosed