Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3549042 | 0.79 | PPARG (0.44) | PPARGPPARAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3546673 | 0.76 | PPARG (0.53) | PPARGPPARAKDM4EALDH1A1MEN1 | |
| SCHEMBL3545746 | 0.75 | MEN1 (0.45) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL3545386 | 0.75 | PPARG (0.55) | PPARGPPARAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3547914 | 0.75 | PPARG (0.52) | PPARGPPARAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL14373003 | 0.72 | TSHR (0.42) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL3554130 | 0.71 | TPMT (0.51) | PPARGPPARAKDM4EALDH1A1MEN1 | |
| SCHEMBL542667 | 0.71 | KDM4E (0.55) | PPARGPPARAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3548975 | 0.71 | CNR2 (0.43) | PPARGPPARAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28113609 | 0.71 | ALOX5 (0.51) | PPARGPPARAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691843-B2 | N-hydroxyamide derivatives possessing antibacterial activity | PFIZER INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20080058304-A1 | N-hydroxyamide derivatives possessing antibacterial activity | VICURON HOLDINGS LLC | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058304-A1 | N-hydroxyamide derivatives possessing antibacterial activity | AMDHD2, OGA, ENGASE | PPARG 4024/4885PPARA 3704/4885KDM4E 2323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.