Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3549511 | 1.00 | FKBP1A (0.44) | FKBP1APDK2GRM5ALDH1A1CYP1A2 | |
| SCHEMBL3548264 | 0.91 | TSHR (0.39) | FKBP1AGRM5ALDH1A1CYP1A2TSHR | |
| SCHEMBL3548261 | 0.91 | TSHR (0.39) | FKBP1AGRM5ALDH1A1CYP1A2TSHR | |
| SCHEMBL3547601 | 0.83 | FKBP1A (0.51) | FKBP1APDK2ALDH1A1CYP1A2MEN1 | |
| SCHEMBL3547600 | 0.83 | FKBP1A (0.51) | FKBP1APDK2ALDH1A1CYP1A2MEN1 | |
| SCHEMBL3544958 | 0.80 | FKBP1A (0.52) | FKBP1APDK2ALDH1A1CYP1A2TSHR | |
| SCHEMBL3544962 | 0.80 | FKBP1A (0.52) | FKBP1APDK2ALDH1A1CYP1A2TSHR | |
| SCHEMBL3546350 | 0.79 | FKBP1A (0.64) | FKBP1APDK2ALDH1A1CYP1A2MEN1 | |
| SCHEMBL3546353 | 0.79 | FKBP1A (0.64) | FKBP1APDK2ALDH1A1CYP1A2MEN1 | |
| SCHEMBL3549639 | 0.78 | AKR1C2 (0.49) | LMNATUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691843-B2 | N-hydroxyamide derivatives possessing antibacterial activity | PFIZER INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20080058304-A1 | N-hydroxyamide derivatives possessing antibacterial activity | VICURON HOLDINGS LLC | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058304-A1 | N-hydroxyamide derivatives possessing antibacterial activity | AMDHD2, OGA, ENGASE | FKBP1A 3069/4885PDK2 2445/4885GRM5 3683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.