⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10643498 | 1.00 | — | — | |
| SCHEMBL18960787 | 1.00 | — | — | |
| SCHEMBL9663942 | 1.00 | — | — | |
| SCHEMBL3549923 | 1.00 | — | — | |
| SCHEMBL9666157 | 1.00 | — | — | |
| Water SCHEMBL10645090 | 0.99 | — | — | |
| Water SCHEMBL10642998 | 0.99 | — | — | |
| Water SCHEMBL10643003 | 0.99 | — | — | |
| Water SCHEMBL10645046 | 0.99 | — | — | |
| Water SCHEMBL10644388 | 0.99 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313980-A1 | LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS | Fedora Pharmaceuticals Inc. (CA) | 2024-02-07 | — | — | EP | claimed |
| WO-2022208356-A1 | LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS | FEDORA PHARMACEUTICALS INC. (CA) | 2022-10-06 | — | — | WO | claimed |
| EP-0291304-B1 | PROCESS FOR THE CONVERSION OF THE E-ISOMER OF 6-(SUBSTITUTED METHYLENE)-2-PENEMS INTO THE Z-ISOMER | BEECHAM GROUP PLC (GB) | 1992-02-26 | — | — | EP | claimed |
| EP-0154132-B1 | 6-ALKYLIDENE PENEMS, THEIR PREPARATION AND USE, AND INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1992-01-08 | — | — | EP | claimed |
| EP-0291304-A1 | Process for the conversion of the E-isomer of 6-(substituted methylene)-2-penems into the Z-isomer | BEECHAM GROUP PLC (GB) | 1988-11-17 | — | — | EP | claimed |
| US-4774238-A | BACTERICIDES, BETA-LACTAMASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1988-09-27 | — | — | US | claimed |
| EP-0210814-A1 | 6-(Substituted methylene) penems | BEECHAM GROUP PLC (GB) | 1987-02-04 | — | — | EP | claimed |
| EP-0154132-A1 | 6-Alkylidene penems, their preparation and use, and intermediates | BEECHAM GROUP PLC (GB) | 1985-09-11 | — | — | EP | claimed |
| US-12274740-B2 | Microbiome protection from oral antibiotics | THERIVA BIOLOGICS, INC. (US) | 2025-04-15 | — | — | US | disclosed |
| US-20240269247-A1 | MICROBIOME PROTECTION FROM ORAL ANTIBIOTICS | THERIVA BIOLOGICS, INC. | 2024-08-15 | — | — | US | disclosed |
| US-20240197842-A1 | METHOD AND COMPOSITIONS FOR INHIBITING OR PREVENTING ADVERSE EFFECTS OF ORAL ANTIBIOTICS | THERIVA BIOLOGICS, INC. | 2024-06-20 | — | — | US | disclosed |
| US-11944669-B2 | Method and compositions for inhibiting or preventing adverse effects of oral antibiotics | THERIVA BIOLOGICS, INC. (US) | 2024-04-02 | — | — | US | disclosed |
| US-20240082370-A1 | SAFE AND EFFECTIVE BETA-LACTAMASE DOSING FOR MICROBIOME PROTECTION | THERIVA BIOLOGICS, INC. | 2024-03-14 | — | — | US | disclosed |
| EP-4313980-A1 | LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS | Fedora Pharmaceuticals Inc. (CA) | 2024-02-07 | — | — | EP | disclosed |
| US-4798828-A | LACTAMASE INHIBITORS | BEECHAM GROUP P.L.C. (GB) | 1989-01-17 | — | — | US | disclosed |
| EP-0291304-A1 | Process for the conversion of the E-isomer of 6-(substituted methylene)-2-penems into the Z-isomer | BEECHAM GROUP PLC (GB) | 1988-11-17 | — | — | EP | disclosed |
| US-4774238-A | BACTERICIDES, BETA-LACTAMASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1988-09-27 | — | — | US | disclosed |
| EP-0232966-A1 | Process for the preparation of penem compounds and intermediates for this preparation | BEECHAM GROUP PLC (GB) | 1987-08-19 | — | — | EP | disclosed |
| EP-0210814-A1 | 6-(Substituted methylene) penems | BEECHAM GROUP PLC (GB) | 1987-02-04 | — | — | EP | disclosed |
| EP-0154132-A1 | 6-Alkylidene penems, their preparation and use, and intermediates | BEECHAM GROUP PLC (GB) | 1985-09-11 | — | — | EP | disclosed |