Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Nitroaniline SCHEMBL6000 | 0.98 | PDE7A (0.62) | PDE7ASMN1; SMN2TDP1ALDH1A1TSHR | |
| 2-Nitroaniline SCHEMBL29396517 | 0.98 | PDE7A (0.62) | PDE7ASMN1; SMN2TDP1ALDH1A1TSHR | |
| 2-Nitroaniline SCHEMBL5331149 | 0.95 | PDE7A (0.60) | PDE7ASMN1; SMN2TDP1ALDH1A1TSHR | |
| 2-Nitroaniline SCHEMBL20876419 | 0.95 | PDE7A (0.60) | PDE7ASMN1; SMN2TDP1ALDH1A1TSHR | |
| 2-Nitroaniline SCHEMBL28878330 | 0.95 | PDE7A (0.60) | PDE7ASMN1; SMN2TDP1ALDH1A1TSHR | |
| 2-Nitroaniline SCHEMBL3094201 | 0.95 | PDE7A (0.60) | PDE7ASMN1; SMN2TDP1ALDH1A1TSHR | |
| 2-Nitroaniline SCHEMBL859788 | 0.95 | PDE7A (0.60) | PDE7ASMN1; SMN2TDP1ALDH1A1TSHR | |
| 2-Nitroaniline SCHEMBL859790 | 0.95 | PDE7A (0.60) | PDE7ASMN1; SMN2TDP1ALDH1A1TSHR | |
| 2-Nitroaniline SCHEMBL5718349 | 0.95 | PDE7A (0.60) | PDE7ASMN1; SMN2TDP1ALDH1A1TSHR | |
| 2-Nitroaniline SCHEMBL28069602 | 0.95 | PDE7A (0.60) | PDE7ASMN1; SMN2TDP1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637703-B2 | Methods for synthesizing ammonia borane | THE OHIO STATE UNIVERSITY (US) | 2014-01-28 | — | — | US | claimed |
| US-8637703-B2 | Methods for synthesizing ammonia borane | THE OHIO STATE UNIVERSITY (US) | 2014-01-28 | — | — | US | disclosed |
| EP-2007743-B1 | METHODS FOR SYNTHESIZING AMMONIA BORANE | UNIV OHIO STATE (US) | 2013-06-12 | — | — | EP | disclosed |
| US-20120014857-A1 | METHODS FOR SYNTHESIZING AMMONIA BORANE | THE OHIO STATE UNIVERSITY (US) | 2012-01-19 | — | — | US | disclosed |
| US-7977508-B2 | Methods for synthesizing ammonia borane | THE OHIO STATE UNIVERSITY (US) | 2011-07-12 | — | — | US | disclosed |
| US-20090104102-A1 | METHODS FOR SYNTHESIZING AMMONIA BORANE | THE OHIO STATE UNIVERSITY | 2009-04-23 | — | — | US | disclosed |
| EP-2007743-A2 | METHODS FOR SYNTHESIZING AMMONIA BORANE | The Ohio State University (US) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007120511-A2 | METHODS FOR SYNTHESIZING AMMONIA BORANE | THE OHIO STATE UNIVERSITY (US) | 2007-10-25 | — | — | WO | disclosed |