Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 20/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3544781 | 0.95 | PLA2G4A (1.00) | PLA2G4A | |
| SCHEMBL1500830 | 0.94 | PLA2G4A (1.00) | PLA2G4A | |
| SCHEMBL1500803 | 0.92 | PLA2G4A (1.00) | PLA2G4A | |
| SCHEMBL1500768 | 0.92 | PLA2G4A (1.00) | PLA2G4A | |
| SCHEMBL2885646 | 0.92 | PLA2G4A (0.88) | PLA2G4A | |
| Ecopladib SCHEMBL29829778 | 0.92 | PLA2G4A (1.00) | PLA2G4A | |
| Ecopladib SCHEMBL1500755 | 0.92 | PLA2G4A (1.00) | PLA2G4A | |
| SCHEMBL1500811 | 0.92 | PLA2G4A (0.87) | PLA2G4A | |
| SCHEMBL83500 | 0.92 | PLA2G4A (1.00) | PLA2G4A | |
| SCHEMBL1500957 | 0.91 | PLA2G4A (0.86) | PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605156-B2 | Methods for the use of inhibitors of cytosolic phospholipase A2 | WYETH (US) | 2009-10-20 | — | — | US | claimed |
| US-7713964-B2 | Methods for treating asthmatic conditions | WYETH LLC (US) | 2010-05-11 | — | — | US | disclosed |
| US-7605156-B2 | Methods for the use of inhibitors of cytosolic phospholipase A2 | WYETH (US) | 2009-10-20 | — | — | US | disclosed |