SCHEMBL3552305

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13341770	0.84	TSHR (0.46)	TSHRCA12CA1CA2CA7
	SCHEMBL7008683	0.83	TSHR (0.44)	TSHRCA12CA1CA2CA7
	SCHEMBL13034140	0.82	ALDH1A1 (0.42)	CA1CA2TDP1ALDH1A1LMNA
	SCHEMBL3552780	0.82	CYP4F2 (0.46)	TSHRCA12CA1CA2CA7
	SCHEMBL2001481	0.81	TSHR (0.52)	TSHRCA12CA1CA2CA7
	SCHEMBL2184188	0.78	TSHR (0.48)	TSHRCA12CA1CA2CA7
	SCHEMBL9032443	0.77	KMT2A (0.41)	CA12CA1CA2CA7CA9
	SCHEMBL7813719	0.76	TSHR (0.52)	TSHRCA12CA1CA2CA7
	SCHEMBL31237092	0.76	TSHR (0.50)	TSHRCA12CA1CA2CA7
	SCHEMBL7589051	0.75	TSHR (0.46)	TSHRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.