SCHEMBL355272

SCHEMBL355272

Cc1cccc(C)c1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
KDM4E B2RXH2 3/20 0.54
ALDH1A1 P00352 3/20 0.54
HPGD P15428 2/20 0.54
HSD17B10 Q99714 2/20 0.54
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
KMT2A Q03164 2/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
MYC P01106 1/20 0.48
FABP3 P05413 1/20 0.46
FABP4 P15090 1/20 0.46
NOTUM Q6P988 1/20 0.44
MCL1 Q07820 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6909100 0.97 TDP1 (0.59) TDP1L3MBTL1KDM4EALDH1A1HPGD
SCHEMBL6913554 0.97 L3MBTL1 (0.59) TDP1L3MBTL1KDM4EALDH1A1HPGD
SCHEMBL6907913 0.97 TDP1 (0.59) TDP1L3MBTL1KDM4EALDH1A1HPGD
SCHEMBL6916441 0.97 TDP1 (0.59) TDP1L3MBTL1KDM4EALDH1A1HPGD
SCHEMBL6916435 0.97 TDP1 (0.59) TDP1L3MBTL1KDM4EALDH1A1HPGD
SCHEMBL11466346 0.97 TDP1 (0.59) TDP1L3MBTL1KDM4EALDH1A1HPGD
Bromide SCHEMBL6113408 0.97 TDP1 (0.59) TDP1L3MBTL1KDM4EALDH1A1HPGD
Hydrochloric Acid SCHEMBL6113042 0.97 TDP1 (0.59) TDP1L3MBTL1KDM4EALDH1A1HPGD
SCHEMBL11079483 0.97 TDP1 (0.59) TDP1L3MBTL1KDM4EALDH1A1HPGD
Iodide SCHEMBL6113169 0.97 TDP1 (0.59) TDP1L3MBTL1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1809 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
CN-114901653-B Novel amide derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof 株式会社LG化学 2024-11-22 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-117801970-A Hansenula polymorpha (Hanseniaspora uvarum) strain 181 with grape juice, application, product and method thereof 宁夏农产品质量标准与检测技术研究所(宁夏农产品质量监测中心) 2024-04-02 CN claimed
CN-114901273-A Pharmaceutical compositions of CASR modulators and methods and uses thereof 鲁平有限公司 2022-08-12 CN claimed
CN-114901653-A Novel amide derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof 株式会社LG化学 2022-08-12 CN claimed
CN-114605306-B Method for synthesizing organic sulfur compound based on alkyl xanthate and application thereof 南京师范大学 2022-07-29 CN claimed
CN-114790136-A Preparation method and application of active trivalent organic chromium compound 中国石油天然气股份有限公司 2022-07-26 CN claimed
CN-111620832-B Multi-substituted oxazoline compound and preparation method thereof 南京工业大学 2022-07-05 CN claimed
US-6398857-B1 ACCUSTIC PIEZOELECTRIC; HOT MELT INK JET PRINTING; BENZOIC ACID VEHICLE; ALKYL OR PHENYL CARBOXYLIC ACID VISCOSITY MODIFIER; RETAINS DESIRED HARDNESS XEROX CORPORATION 2002-06-04 US claimed
US-20010007038-A1 Catalyst and method for amide formation SCOTT WILLIAM LEONARD (US) 2001-07-05 US claimed
EP-1045835-A1 CATALYST AND METHOD FOR AMIDE FORMATION ELI LILLY AND COMPANY (US) 2000-10-25 EP claimed
US-6121471-A Catalyst and method for amide formation ELI LILLY AND COMPANY (US) 2000-09-19 US claimed
WO-1999032444-A1 CATALYST AND METHOD FOR AMIDE FORMATION ELI LILLY AND COMPANY (US) 1999-07-01 WO claimed
CN-1180739-A Health-care wine and preparation method thereof XU BAOSHI (CN) 1998-05-06 CN claimed
EP-0507576-A1 Polypropylene-based resin compositions TOSOH CORPORATION (JP) 1992-10-07 EP claimed
EP-0187462-B1 SUPPORTED OLEFIN POLYMERIZATION CATALYST AMOCO CORPORATION (US) 1990-04-25 EP claimed
EP-0169650-A2 Process for preparing aromatic urethanes from nitroaromatic compounds Montedison S.p.A. (IT) 1986-01-29 EP claimed
US-4154921-A REDUCE FORMATION OF SCALE BY ADDITION OF A HINDERED BENZOIC ACID INCLUDING 2,6-DICHLORO-, 2,6-DIMETHYL-, AND 2,4,6-TRIMETHYL-/; E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-05-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010007038-A1 Catalyst and method for amide formation HAT1, MOGAT2, H1-2 TDP1 2295/4885L3MBTL1 2546/4885KDM4E 2266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.