Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3553696 | 1.00 | HTR2C (0.46) | HTR2CHTR2BNPC1RAB9ACTSC | |
| Trifluoroacetic Acid SCHEMBL9251606 | 0.90 | CTSC (0.41) | HTR2CHTR2BNPC1RAB9ACTSC | |
| Hydrochloric Acid SCHEMBL3545786 | 0.84 | HTR2C (0.60) | HTR2CHTR2BNPC1RAB9ACTSC | |
| Hydrochloric Acid SCHEMBL3545785 | 0.84 | HTR2C (0.60) | HTR2CHTR2BNPC1RAB9ACTSC | |
| SCHEMBL8304205 | 0.81 | NPC1 (0.43) | HTR2CHTR2BNPC1RAB9ACTSC | |
| SCHEMBL8304207 | 0.81 | NPC1 (0.43) | HTR2CHTR2BNPC1RAB9ACTSC | |
| Trifluoroacetic Acid SCHEMBL29447618 | 0.80 | TSHR (0.52) | HTR2CHTR2BNPC1RAB9AF2 | |
| Trifluoroacetic Acid SCHEMBL11211637 | 0.80 | TSHR (0.52) | HTR2CHTR2BNPC1RAB9AF2 | |
| Trifluoroacetic Acid SCHEMBL3899980 | 0.78 | NPC1 (0.43) | NPC1RAB9AF2EPHX2 | |
| Trifluoroacetic Acid SCHEMBL10518928 | 0.76 | HTR2C (0.57) | HTR2CHTR2BCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691843-B2 | N-hydroxyamide derivatives possessing antibacterial activity | PFIZER INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20080058304-A1 | N-hydroxyamide derivatives possessing antibacterial activity | VICURON HOLDINGS LLC | 2008-03-06 | — | — | US | disclosed |
| EP-1539744-A4 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARM INC (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1539744-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004007444-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058304-A1 | N-hydroxyamide derivatives possessing antibacterial activity | AMDHD2, OGA, ENGASE | HTR2C 1737/4885HTR2B 1401/4885NPC1 3597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.