Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304207 | 1.00 | NPC1 (0.43) | NPC1RAB9AHTR2CHTR2BCTSC | |
| Trifluoroacetic Acid SCHEMBL9251606 | 0.93 | CTSC (0.41) | NPC1RAB9AHTR2CHTR2BCTSC | |
| Trifluoroacetic Acid SCHEMBL3553696 | 0.81 | HTR2C (0.46) | NPC1RAB9AHTR2CHTR2BCTSC | |
| Trifluoroacetic Acid SCHEMBL3553698 | 0.81 | HTR2C (0.46) | NPC1RAB9AHTR2CHTR2BCTSC | |
| Hydrochloric Acid SCHEMBL3545786 | 0.81 | HTR2C (0.60) | NPC1RAB9AHTR2CHTR2BCTSC | |
| Hydrochloric Acid SCHEMBL3545785 | 0.81 | HTR2C (0.60) | NPC1RAB9AHTR2CHTR2BCTSC | |
| SCHEMBL1576471 | 0.81 | TSHR (0.57) | HTR2CHTR2BTSHRCPB1 | |
| SCHEMBL7996223 | 0.81 | TSHR (0.57) | HTR2CHTR2BTSHRCPB1 | |
| SCHEMBL7994521 | 0.81 | TSHR (0.57) | HTR2CHTR2BTSHRCPB1 | |
| SCHEMBL23491956 | 0.80 | MASP2 (0.53) | HTR2CHTR2BCTSCMASP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614986-B1 | Enzymatic racemate cleavage of 2-pipéridine alkylcarboxylates | SYNTHELABO (FR) | 1999-07-21 | — | — | EP | disclosed |
| EP-0565396-B1 | 1-[2-(arylsulfonylamino)-1-oxoethyl]piperidine derivatives, their preparation and use in therapy | SYNTHELABO (FR) | 1998-01-07 | — | — | EP | disclosed |
| EP-0614986-A1 | Enzymatic racemate cleavage of 2-pipéridine alkylcarboxylates and their use as synthesis intermediates | SYNTHELABO (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0565396-A1 | 1-(2-arylsulfonylamino)-1-oxoethyl)-piperidine derivatives, their preparation and use in therapy | SYNTHELABO (FR) | 1993-10-13 | — | — | EP | disclosed |