SCHEMBL355404

SCHEMBL355404

C=CCC(CO)(CO)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
ALDH1A1 P00352 2/20 0.42
HTT P42858 1/20 0.35
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
LMNA P02545 1/20 0.32
ABCC4 O15439 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2732854 0.89 TSHR (0.45) TSHRALDH1A1HTTLMNAABCC4
SCHEMBL20955857 0.83 ALDH1A1 (0.35) TSHRALDH1A1HTT
SCHEMBL20955858 0.83 ALDH1A1 (0.35) TSHRALDH1A1HTT
SCHEMBL7252450 0.80 ALDH1A1 (0.39) TSHRALDH1A1HTT
SCHEMBL1716936 0.80 ALDH1A1 (0.39) TSHRALDH1A1HTT
SCHEMBL16823397 0.80 ALDH1A1 (0.39) TSHRALDH1A1HTTHIF1AABCC4
SCHEMBL4616913 0.80 ALDH1A1 (0.39) TSHRALDH1A1HTT
Hydrochloric Acid SCHEMBL11351345 0.78 ALDH1A1 (0.38) TSHRALDH1A1HTTHIF1AABCC4
Hydrochloric Acid SCHEMBL11876600 0.78 ALDH1A1 (0.38) TSHRALDH1A1HTT
SCHEMBL176385 0.76 ALDH1A1 (0.35) TSHRALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2089452-B8 PROCESS FOR OBTAINING INCREASED MOLECULAR WEIGHT OF A POLYMER AND THE USE OF SAID POLYMER PERSTORP SPECIALTY CHEM AB (SE) 2012-09-26 EP claimed
EP-2089452-B1 PROCESS FOR OBTAINING INCREASED MOLECULAR WEIGHT OF A POLYMER AND THE USE OF SAID POLYMER PERSTORP SPECIALTY CHEM AB (SE) 2012-07-11 EP claimed
EP-2089452-A1 PROCESS FOR OBTAINING INCREASED MOLECULAR WEIGHT OF A POLYMER AND THE USE OF SAID POLYMER Perstorp Specialty Chemicals AB (SE) 2009-08-19 EP claimed
US-20090069527-A1 AIR DRYING POLYMER PERSTORP SPECIALTY CHEMICALS (AB) (SE) 2009-03-12 US claimed
WO-2008069725-A1 PROCESS FOR OBTAINING INCREASED MOLECULAR WEIGHT OF A POLYMER AND THE USE OF SAID POLYMER PERSTORP SPECIALTY CHEMICALS AB (SE) 2008-06-12 WO claimed
EP-1869101-A1 AIR DRYING POLYMER Perstorp Specialty Chemicals AB (SE) 2007-12-26 EP claimed
WO-2006118532-A1 HYBRID RADIATION CURABLE COMPOSITION AND USE THEREOF PERSTORP SPECIALTY CHEMICALS AB (SE) 2006-11-09 WO claimed
WO-2006110075-A1 AIR DRYING POLYMER PERSTORP SPECIALTY CHEMICALS AB (SE) 2006-10-19 WO claimed
EP-2560976-B9 FUROPYRIDINE COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2017-06-07 EP disclosed
EP-2560976-B9 FUROPYRIDINE COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2017-06-07 EP disclosed
EP-2560976-B1 FUROPYRIDINE COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2016-08-24 EP disclosed
EP-2560976-B1 FUROPYRIDINE COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2016-08-24 EP disclosed
US-9249275-B2 Polyionic dendrimer and hydrogel comprising same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2016-02-02 US disclosed
US-20140221292-A1 POLYIONIC DENDRIMER AND HYDROGEL COMPRISING SAME JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2014-08-07 US disclosed
EP-0772642-A1 STRONG CARBOXYLIC ACID FUNCTIONAL POLYURETHANE POLYMERS AND BLENDS THEREOF USED IN MAGNETIC RECORDING MEDIA MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-05-14 EP disclosed
US-5512651-A POLYESTERURETHANE COPOLYMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-04-30 US disclosed
US-5498685-A REACTION WITH POLAR-FUNCTIONAL DICARBOXYLIC ACID ANHYDRIDES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-03-12 US disclosed
WO-1996004326-A1 STRONG CARBOXYLIC ACID FUNCTIONAL POLYURETHANE POLYMERS AND BLENDS THEREOF USED IN MAGNETIC RECORDING MEDIA MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-02-15 WO disclosed
EP-0696295-A1 CARBOXYLIC-ACID FUNCTIONAL POLYURETHANE POLYMERS AND THEIR USE IN MAGNETIC RECORDING MEDIA MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-02-14 EP disclosed
WO-1994025500-A1 CARBOXYLIC-ACID FUNCTIONAL POLYURETHANE POLYMERS AND THEIR USE IN MAGNETIC RECORDING MEDIA MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140221292-A1 POLYIONIC DENDRIMER AND HYDROGEL COMPRISING SAME CD44, PCNA, GMNN TSHR 999/4885ALDH1A1 2155/4885HTT 1167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.