Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 11/20 | 0.78 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551560 | 0.90 | ADORA1 (0.62) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3549098 | 0.88 | ADORA1 (0.72) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3539872 | 0.85 | ADORA1 (0.69) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6444638 | 0.82 | ADORA1 (0.65) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3552401 | 0.82 | ADORA1 (0.64) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3552614 | 0.81 | ADORA1 (0.52) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3551969 | 0.80 | ADORA1 (0.53) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6105552 | 0.79 | ADORA1 (0.69) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13848718 | 0.79 | ADORA1 (0.59) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL12992732 | 0.78 | ADORA1 (0.71) | ADORA1ADORA2AALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855219-B2 | Substituted 2-oxy-3,5-dicyano-4aryl-6-aminopyridines and use thereof | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-21 | — | — | US | disclosed |
| US-7855219-B2 | Substituted 2-oxy-3,5-dicyano-4aryl-6-aminopyridines and use thereof | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-21 | — | — | US | disclosed |
| US-7855219-B2 | Substituted 2-oxy-3,5-dicyano-4aryl-6-aminopyridines and use thereof | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-21 | — | — | US | disclosed |
| EP-1368320-B1 | SUBSTITUTED 2-OXY-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-08-16 | — | — | EP | disclosed |
| US-20050261502-A1 | Substituted 2-oxy-3,5-dicyano-4-aryl-6-aminopyridines and use thereof | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-11-24 | — | — | US | disclosed |
| EP-1368320-A1 | SUBSTITUTED 2-OXY-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002070484-A1 | SUBSTITUTED 2-OXY-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261502-A1 | Substituted 2-oxy-3,5-dicyano-4-aryl-6-aminopyridines and use thereof | ADORA2A, ADORA3, ADORA1 | ADORA1 3/4885ADORA2A 1/4885ALDH1A1 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.