Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558409 | 0.81 | HDAC1 (0.52) | HDAC1HDAC8HDAC6ALDH1A1ROCK2 | |
| SCHEMBL3436258 | 0.80 | ALDH1A1 (0.47) | HDAC1HDAC8HDAC6ALDH1A1PDE4B | |
| SCHEMBL6386434 | 0.79 | HDAC1 (0.65) | HDAC1HDAC8HDAC6ALDH1A1PDE4B | |
| SCHEMBL18723081 | 0.79 | HDAC1 (0.44) | HDAC1HDAC8HDAC6ALDH1A1ROCK2 | |
| SCHEMBL21689281 | 0.78 | HDAC1 (0.68) | HDAC1HDAC8HDAC6ALDH1A1PDE4B | |
| SCHEMBL3546224 | 0.78 | HDAC1 (0.46) | HDAC1HDAC8HDAC6ALDH1A1ROCK2 | |
| SCHEMBL31482450 | 0.77 | CSNK2A1 (0.39) | HDAC1HDAC8HDAC6ALDH1A1ROCK2 | |
| SCHEMBL25002914 | 0.77 | HDAC1 (0.74) | HDAC1HDAC8HDAC6ALDH1A1PDE4B | |
| SCHEMBL17487352 | 0.77 | HDAC1 (0.67) | HDAC1HDAC8HDAC6ALDH1A1PDE4B | |
| SCHEMBL21639144 | 0.77 | HDAC1 (0.68) | HDAC1HDAC8HDAC6ALDH1A1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | HDAC1 372/4885HDAC8 384/4885HDAC6 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.