Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 13/20 | 0.72 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.36 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546033 | 0.84 | ERN1 (1.00) | ERN1SRCPIM1SELLSELP | |
| SCHEMBL5031416 | 0.82 | ERN1 (0.95) | ERN1SRCPIM1SELLSELP | |
| SCHEMBL3982574 | 0.78 | ERN1 (0.78) | ERN1SRCPIM1SELLSELP | |
| SCHEMBL29957335 | 0.78 | ERN1 (0.78) | ERN1SRCPIM1SELLSELP | |
| SCHEMBL2788053 | 0.78 | ERN1 (0.78) | ERN1SRCPIM1SELLSELP | |
| SCHEMBL11408969 | 0.77 | ERN1 (0.75) | ERN1SRCPIM1SELLSELP | |
| SCHEMBL13342004 | 0.77 | SELL (0.50) | ERN1SELLSELPSELE | |
| SCHEMBL9621407 | 0.75 | ERN1 (0.72) | ERN1SRC | |
| SCHEMBL11798787 | 0.75 | ERN1 (0.72) | ERN1SRCPIM1GRK6SELL | |
| SCHEMBL13855816 | 0.75 | ERN1 (0.72) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307372-B1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2012-04-25 | — | — | EP | disclosed |