SCHEMBL13342004

SCHEMBL13342004

Bc1cc(C)cc(B)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SELL P14151 1/20 0.50
SELP P16109 1/20 0.50
SELE P16581 1/20 0.50
ALDH1A1 P00352 5/20 0.45
ACHE P22303 4/20 0.43
POLB P06746 2/20 0.42
CA2 P00918 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TYR P14679 1/20 0.42
KDM4E B2RXH2 2/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
APEX1 P27695 1/20 0.41
MPI P34949 1/20 0.41
RECQL P46063 1/20 0.41
KMT2A Q03164 1/20 0.41
LMNA P02545 1/20 0.40
ERN1 O75460 1/20 0.40
GPR35 Q9HC97 1/20 0.37
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14016309 0.86 ALDH1A1 (0.52) SELLSELPSELEALDH1A1ACHE
SCHEMBL25925637 0.82 SELL (0.40) SELLSELPSELEALDH1A1ACHE
SCHEMBL14392219 0.82 CA2 (0.42) SELLSELPSELEALDH1A1ACHE
SCHEMBL13772784 0.78 AMY1A (0.38) SELLSELPSELEALDH1A1ACHE
SCHEMBL3554507 0.77 ERN1 (0.72) SELLSELPSELEERN1
SCHEMBL3524436 0.73 GLA (0.46) SELLSELPSELEALDH1A1GAA
SCHEMBL18976628 0.73 CA1 (0.40) CA2CA1
SCHEMBL23080309 0.73 ACHE (0.37) SELLSELPSELEALDH1A1ACHE
SCHEMBL20682673 0.73 ALDH1A1 (0.37) SELLSELPSELEALDH1A1ACHE
SCHEMBL8354030 0.73 ACHE (0.40) SELLSELPSELEALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3490999-B1 SYNTHESIS OF M-TERPHENYL PENDANT BIS-ETHER LIGANDS AND METAL COMPLEX AND THEIR USE IN OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2021-04-14 EP disclosed
WO-2018022871-A1 SYNTHESIS OF m-TERPHENYL PENDANT BIS-ETHER LIGANDS AND METAL COMPLEX AND THEIR USE IN OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2018-02-01 WO disclosed
EP-2121621-B1 LXR AND FXR MODULATORS EXELIXIS PATENT CO LLC (US) 2014-05-07 EP disclosed
EP-2192212-A1 Flame-retardant polyester fibers for artificial hair Kaneka Corporation (JP) 2010-06-02 EP disclosed
EP-1863791-B1 2-OXO-1,2,4,5-TETRAHYDRO-1,3-BENZODIAZEPIN-3-YL-PIPERIDINES USED AS CGRP ANTAGONISTS BOEHRINGER INGELHEIM INT (DE) 2008-11-12 EP disclosed
EP-1626999-B1 OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS EXXONMOBIL CHEM PATENTS INC (US) 2007-09-26 EP disclosed