Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13403212 | 0.92 | AVPR1A (0.85) | AVPR1AAVPR2 | |
| SCHEMBL7332293 | 0.91 | AVPR1A (0.83) | AVPR1AAVPR2 | |
| SCHEMBL3556377 | 0.90 | AVPR1A (0.81) | AVPR1AAVPR2 | |
| SCHEMBL4147095 | 0.89 | AVPR1A (0.82) | AVPR1AAVPR2 | |
| SCHEMBL7314707 | 0.88 | AVPR1A (1.00) | AVPR1AAVPR2 | |
| SCHEMBL4145424 | 0.88 | AVPR1A (0.79) | AVPR1AAVPR2 | |
| SCHEMBL6624843 | 0.87 | AVPR1A (0.77) | AVPR1AAVPR2 | |
| SCHEMBL7312839 | 0.87 | AVPR1A (0.77) | AVPR1AAVPR2 | |
| SCHEMBL6068819 | 0.87 | AVPR1A (0.77) | AVPR1AAVPR2 | |
| SCHEMBL6625491 | 0.87 | AVPR1A (0.77) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805813-B1 | TRICYCLIC VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID CO (US) | 2002-05-15 | — | — | EP | claimed |
| WO-1996022292-A1 | TRICYCLIC VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | claimed |
| US-5521173-A | TREATING DISEASES CHARACTERIZED BY EXCESS RENAL REABSORPTION OF WATER | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-05-28 | — | — | US | claimed |
| US-7678787-B2 | Pyrrolobenzodiazepine pyridine carboxamides and derivatives as follicle-stimulating hormone receptor antagonists | WYETH (US) | 2010-03-16 | — | — | US | disclosed |
| EP-1893615-A1 | PYRROLOBENZODIAZEPINE PYRIDINE CARBOXAMIDES AND DERIVATIVES AS FOLLICLE-STIMULATING HORMONE RECEPTOR ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2008-03-05 | — | — | EP | disclosed |
| US-20060287522-A1 | Pyrrolobenzodiazepine pyridine carboxamides and derivatives as follicle-stimulating hormone receptor antagonists | WYETH (US) | 2006-12-21 | — | — | US | disclosed |
| WO-2006135687-A1 | PYRROLOBENZODIAZEPINE PYRIDINE CARBOXAMIDES AND DERIVATIVES AS FOLLICLE-STIMULATING HORMONE RECEPTOR ANTAGONISTS | WYETH (US) | 2006-12-21 | — | — | WO | disclosed |
| US-20060258644-A1 | Pyrrolobenzodiazepines and heteroaryl, aryl and cycloalkylamino ketone derivatives as follicle stimulating hormone receptor (FSH-R) antagonists | WYETH (US) | 2006-11-16 | — | — | US | disclosed |
| EP-0805813-B1 | TRICYCLIC VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID CO (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-1996022292-A1 | TRICYCLIC VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |
| US-5521173-A | TREATING DISEASES CHARACTERIZED BY EXCESS RENAL REABSORPTION OF WATER | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258644-A1 | Pyrrolobenzodiazepines and heteroaryl, aryl and cycloalkylamino ketone derivatives as follicle stimulating hormone receptor (FSH-R) antagonists | FSHR, GNRHR, PRLHR | AVPR1A 30/4885AVPR2 13/4885 |
| US-20060287522-A1 | Pyrrolobenzodiazepine pyridine carboxamides and derivatives as follicle-stimulating hormone receptor antagonists | FSHR, GNRHR, PRLHR | AVPR1A 51/4885AVPR2 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.