Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13403212 | 0.89 | AVPR1A (0.85) | AVPR1AAVPR2 | |
| SCHEMBL7332293 | 0.88 | AVPR1A (0.83) | AVPR1AAVPR2 | |
| SCHEMBL3554976 | 0.87 | AVPR1A (1.00) | AVPR1AAVPR2 | |
| SCHEMBL5738429 | 0.87 | AVPR1A (0.77) | AVPR1AAVPR2 | |
| SCHEMBL3556377 | 0.87 | AVPR1A (0.81) | AVPR1AAVPR2 | |
| SCHEMBL6624843 | 0.87 | AVPR1A (0.77) | AVPR1AAVPR2 | |
| SCHEMBL6625491 | 0.87 | AVPR1A (0.77) | AVPR1AAVPR2 | |
| SCHEMBL6068819 | 0.87 | AVPR1A (0.77) | AVPR1AAVPR2 | |
| SCHEMBL7311596 | 0.84 | AVPR1A (0.66) | AVPR1AAVPR2 | |
| SCHEMBL7332271 | 0.84 | AVPR1A (0.72) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805813-B1 | TRICYCLIC VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID CO (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-1996022292-A1 | TRICYCLIC VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |
| US-5521173-A | TREATING DISEASES CHARACTERIZED BY EXCESS RENAL REABSORPTION OF WATER | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |