SCHEMBL355602

SCHEMBL355602

CCCCCCCc1ccccc1C(CCCCC)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 11/20 0.63
CYSLTR1 Q9Y271 11/20 0.63
BID P55957 3/20 0.51
MCL1 Q07820 3/20 0.51
BCL2L1 Q07817 2/20 0.51
BAK1 Q16611 2/20 0.51
KAT8 Q9H7Z6 2/20 0.51
PPARG P37231 1/20 0.51
PPARA Q07869 1/20 0.51
EP300 Q09472 1/20 0.51
KAT2A Q92830 1/20 0.51
KAT2B Q92831 1/20 0.51
KAT5 Q92993 1/20 0.51
SAE1 Q9UBE0 1/20 0.51
LIPG Q9Y5X9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5385320 1.00 CYSLTR2 (0.63) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL10869942 1.00 CYSLTR2 (0.63) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL11305177 1.00 CYSLTR2 (0.63) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL28570457 1.00 CYSLTR2 (0.63) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL8845786 0.97 CYSLTR2 (0.59) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL8845869 0.97 CYSLTR2 (0.59) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL20564046 0.91 CYSLTR2 (0.51) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL20564521 0.91 CYSLTR2 (0.51) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL27464178 0.90 CYSLTR2 (0.50) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL8669210 0.88 CYSLTR2 (0.49) CYSLTR2CYSLTR1BIDMCL1BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2707470-B1 AROMATIC IMIDES AS LUBRICANT ADDITIVES LUBRIZOL CORP (US) 2021-04-21 EP disclosed
EP-2398873-B1 AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS LUBRIZOL CORP (US) 2017-04-05 EP disclosed
EP-2430134-B1 METHOD USING IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS LUBRIZOL CORP (US) 2016-03-16 EP disclosed
US-9006156-B2 Imides and bis-imides as friction modifiers in lubricants THE LUBRIZOL CORPORATION (US) 2015-04-14 US disclosed
EP-2398876-B1 OXALIC ACID BIS-AMIDES OR AMIDE-ESTER AS FRICTION MODIFIERS IN LUBRICANTS LUBRIZOL CORP (US) 2014-11-19 EP disclosed
US-8778858-B2 Amine derivatives as friction modifiers in lubricants THE LUBRIZOL CORPORATION (US) 2014-07-15 US disclosed
EP-2707470-A1 AROMATIC IMIDES AND ESTERS AS LUBRICANT ADDITIVES The Lubrizol Corporation (US) 2014-03-19 EP disclosed
EP-2406358-B1 AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS LUBRIZOL CORP (US) 2013-08-21 EP disclosed
US-8501674-B2 Amine derivatives as friction modifiers in lubricants THE LUBRIZOL CORPORATION (US) 2013-08-06 US disclosed
WO-2012154708-A1 AROMATIC IMIDES AND ESTERS AS LUBRICANT ADDITIVES THE LUBRIZOL CORPORATION (US) 2012-11-15 WO disclosed
EP-2430134-A1 IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS The Lubrizol Corporation (US) 2012-03-21 EP disclosed
US-20120021958-A1 Oxalic Acid Bis-Amides or Amide-Ester as Friction Modifiers in Lubricants THE LUBRIZOL CORPORATION (US) 2012-01-26 US disclosed
US-20120015855-A1 Amine Derivatives as Friction Modifiers in Lubricants THE LUBRIZOL CORPORATION 2012-01-19 US disclosed
EP-2406358-A1 AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS The Lubrizol Corporation (US) 2012-01-18 EP disclosed
EP-2398873-A1 AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS The Lubrizol Corporation (US) 2011-12-28 EP disclosed
WO-2010132318-A1 IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS THE LUBRIZOL CORPORATION (US) 2010-11-18 WO disclosed
WO-2010096325-A1 AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS THE LUBRIZOL CORPORATION (US) 2010-08-26 WO disclosed
WO-2010096321-A1 OXALIC ACID BIS-AMIDES OR AMIDE-ESTER AS FRICTION MODIFIERS IN LUBRICANTS THE LUBRIZOL CORPORATION (US) 2010-08-26 WO disclosed
WO-2010096318-A1 AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS THE LUBRIZOL CORPORATION (US) 2010-08-26 WO disclosed
US-20100210490-A1 Amine Derivatives as Friction Modifiers in Lubricants THE LUBRIZOL CORPORATION (US) 2010-08-19 US disclosed