SCHEMBL8845786

SCHEMBL8845786

CCCCCCCCCCCCC(C(=O)O)c1ccccc1CCCC

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 10/20 0.59
CYSLTR1 Q9Y271 10/20 0.59
BID P55957 3/20 0.48
MCL1 Q07820 3/20 0.48
BCL2L1 Q07817 2/20 0.48
BAK1 Q16611 2/20 0.48
KAT8 Q9H7Z6 2/20 0.48
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48
EP300 Q09472 1/20 0.48
KAT2A Q92830 1/20 0.48
KAT2B Q92831 1/20 0.48
KAT5 Q92993 1/20 0.48
SAE1 Q9UBE0 1/20 0.48
LIPG Q9Y5X9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8845869 1.00 CYSLTR2 (0.59) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL11305177 0.97 CYSLTR2 (0.63) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL10869942 0.97 CYSLTR2 (0.63) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL355602 0.97 CYSLTR2 (0.63) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL5385320 0.97 CYSLTR2 (0.63) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL28570457 0.97 CYSLTR2 (0.63) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL20564521 0.91 CYSLTR2 (0.51) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL20564046 0.91 CYSLTR2 (0.51) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL28969842 0.91 CYSLTR2 (0.55) CYSLTR2CYSLTR1BIDMCL1BCL2L1
SCHEMBL27464178 0.90 CYSLTR2 (0.50) CYSLTR2CYSLTR1BIDMCL1BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0790824-A1 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE Roche Diagnostics GmbH (DE) 1997-08-27 EP disclosed
WO-1996015784-A2 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE BOEHRINGER MANNHEIM GMBH (DE) 1996-05-30 WO disclosed