SCHEMBL355604

SCHEMBL355604

CCCCCCCC(CCCCC)(C(=O)O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
TSHR P16473 1/20 0.49
GAA P10253 1/20 0.46
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
SCN5A Q14524 3/20 0.46
SCN9A Q15858 3/20 0.46
CETP P11597 3/20 0.45
NAAA Q02083 1/20 0.45
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44
KIF11 P52732 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10869954 1.00 ALDH1A1 (0.49) ALDH1A1TSHRGAACES2CES1
SCHEMBL28570454 1.00 ALDH1A1 (0.49) ALDH1A1TSHRGAACES2CES1
SCHEMBL5385328 1.00 ALDH1A1 (0.49) ALDH1A1TSHRGAACES2CES1
SCHEMBL11305185 1.00 ALDH1A1 (0.49) ALDH1A1TSHRGAACES2CES1
SCHEMBL28018022 0.98 ALDH1A1 (0.47) ALDH1A1TSHRGAACES2CES1
SCHEMBL17749017 0.98 ALDH1A1 (0.50) ALDH1A1TSHRGAACES2CES1
SCHEMBL28002877 0.96 ALDH1A1 (0.46) ALDH1A1TSHRGAACES2CES1
SCHEMBL8904460 0.96 ALDH1A1 (0.46) ALDH1A1TSHRGAACES2CES1
SCHEMBL8904062 0.95 ALDH1A1 (0.47) ALDH1A1TSHRGAACES2CES1
SCHEMBL8666773 0.93 ALDH1A1 (0.44) ALDH1A1TSHRGAACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2707470-B1 AROMATIC IMIDES AS LUBRICANT ADDITIVES LUBRIZOL CORP (US) 2021-04-21 EP disclosed
EP-2398873-B1 AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS LUBRIZOL CORP (US) 2017-04-05 EP disclosed
CN-102395661-B In the lubricant as the amine derivative of friction improver 路博润公司 2017-03-15 CN disclosed
EP-2430134-B1 METHOD USING IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS LUBRIZOL CORP (US) 2016-03-16 EP disclosed
CN-103534341-B As aromatic imide and the ester of lubricant additive THE LUBRIZOL CORP. (US) 2015-12-09 CN disclosed
US-9006156-B2 Imides and bis-imides as friction modifiers in lubricants THE LUBRIZOL CORPORATION (US) 2015-04-14 US disclosed
CN-102803449-B Imides and bisamides as friction modifiers in lubricants LUBRIZOL CORP 2015-02-11 CN disclosed
CN-102395662-B Amine derivatives as friction modifiers in lubricants LUBRIZOL CORP 2015-02-11 CN disclosed
EP-2398876-B1 OXALIC ACID BIS-AMIDES OR AMIDE-ESTER AS FRICTION MODIFIERS IN LUBRICANTS LUBRIZOL CORP (US) 2014-11-19 EP disclosed
US-8778858-B2 Amine derivatives as friction modifiers in lubricants THE LUBRIZOL CORPORATION (US) 2014-07-15 US disclosed
EP-2430134-A1 IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS The Lubrizol Corporation (US) 2012-03-21 EP disclosed
US-20120021958-A1 Oxalic Acid Bis-Amides or Amide-Ester as Friction Modifiers in Lubricants THE LUBRIZOL CORPORATION (US) 2012-01-26 US disclosed
US-20120015855-A1 Amine Derivatives as Friction Modifiers in Lubricants THE LUBRIZOL CORPORATION 2012-01-19 US disclosed
EP-2406358-A1 AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS The Lubrizol Corporation (US) 2012-01-18 EP disclosed
EP-2398873-A1 AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS The Lubrizol Corporation (US) 2011-12-28 EP disclosed
WO-2010132318-A1 IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS THE LUBRIZOL CORPORATION (US) 2010-11-18 WO disclosed
WO-2010096325-A1 AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS THE LUBRIZOL CORPORATION (US) 2010-08-26 WO disclosed
WO-2010096321-A1 OXALIC ACID BIS-AMIDES OR AMIDE-ESTER AS FRICTION MODIFIERS IN LUBRICANTS THE LUBRIZOL CORPORATION (US) 2010-08-26 WO disclosed
WO-2010096318-A1 AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS THE LUBRIZOL CORPORATION (US) 2010-08-26 WO disclosed
US-20100210490-A1 Amine Derivatives as Friction Modifiers in Lubricants THE LUBRIZOL CORPORATION (US) 2010-08-19 US disclosed