⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30957004 | 0.86 | FAAH (0.42) | — | |
| SCHEMBL14150381 | 0.85 | FAAH (0.37) | — | |
| SCHEMBL3556461 | 0.83 | FAAH (0.38) | — | |
| SCHEMBL6420398 | 0.80 | — | — | |
| SCHEMBL9661123 | 0.79 | — | — | |
| SCHEMBL2987191 | 0.78 | — | — | |
| SCHEMBL4812707 | 0.78 | — | — | |
| SCHEMBL349333 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL38661995 | 0.76 | CHRM1 (0.42) | — | |
| SCHEMBL31219183 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104974188-A | Tenofovir disoproxil crystal form and preparation method thereof | ZHEJIANG JIUZHOU PHARM CO LTD | 2015-10-14 | — | — | CN | claimed |
| CN-104974188-B | A kind of tenofovir disoproxil crystal form and preparation method thereof | 浙江九洲药业股份有限公司 | 2019-01-08 | — | — | CN | disclosed |
| CN-104974188-A | Tenofovir disoproxil crystal form and preparation method thereof | ZHEJIANG JIUZHOU PHARM CO LTD | 2015-10-14 | — | — | CN | disclosed |
| CN-101463045-B | Thiophosphate nucleotide compound | HEFEI HENGXING PHARMACEUTICAL INST | 2011-08-31 | — | — | CN | disclosed |
| CN-101921294-A | Substituted benzodihydropyran derivatives and anti-tumor application thereof | ANHUI HUAKANG MEDICINE TECHNOLOGY DEV CO LTD | 2010-12-22 | — | — | CN | disclosed |
| US-7737273-B2 | Process for acyclic phosphonate nucleotide analogs | HETERO DRUGS LIMITED (IN) | 2010-06-15 | — | — | US | disclosed |
| US-7737273-B2 | Process for acyclic phosphonate nucleotide analogs | HETERO DRUGS LIMITED (IN) | 2010-06-15 | — | — | US | disclosed |
| CN-101463045-A | Thiophosphate nucleotide compound | HEFEI HENGXING PHARMACEUTICAL (CN) | 2009-06-24 | — | — | CN | disclosed |
| US-20090012292-A1 | NOVEL PROCESS FOR ACYCLIC PHOSPHONATE NUCLEOTIDE ANALOGS | HETERO DRUGS LIMITED (IN) | 2009-01-08 | — | — | US | disclosed |
| US-20090012292-A1 | NOVEL PROCESS FOR ACYCLIC PHOSPHONATE NUCLEOTIDE ANALOGS | HETERO DRUGS LIMITED (IN) | 2009-01-08 | — | — | US | disclosed |
| EP-1243593-A2 | Nucleotide analog composition and synthesis method | GILEAD SCIENCES, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| US-6069249-A | CHEMICAL INTERMEDIATES; DETECTION LABELS FOR NUCLEOTIDE PROBES | GILEAD SCIENCES, INC. (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0998480-A1 | NUCLEOTIDE ANALOG COMPOSITION AND SYNTHESIS METHOD | GILEAD SCIENCES, INC. (US) | 2000-05-10 | — | — | EP | disclosed |
| US-6043230-A | Use of tenofovir disoproxil fumarate in treatment of HIV | GILEAD SCIENCES, INC. (US) | 2000-03-28 | — | — | US | disclosed |
| US-5977089-A | ORALLY ADMINISTERING TENOFOVIR DERIVATIVES | GILEAD SCIENCES, INC. (US) | 1999-11-02 | — | — | US | disclosed |
| US-5935946-A | TENOFOVIR DISOPROXIL FUMARATE; ANTIVIRAL THERAPY | GILEAD SCIENCES, INC. (US) | 1999-08-10 | — | — | US | disclosed |
| US-5922695-A | COMPOUNDS CONTAINING CARBONATE OR CARBAMATE GROUPS | GILEAD SCIENCES, INC. (US) | 1999-07-13 | — | — | US | disclosed |
| EP-0915894-A1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1999005150-A1 | NUCLEOTIDE ANALOG COMPOSITION AND SYNTHESIS METHOD | GILEAD SCIENCES, INC. (US) | 1999-02-04 | — | — | WO | disclosed |
| WO-1998004569-A1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1998-02-05 | — | — | WO | disclosed |