SCHEMBL35566

SCHEMBL35566

CCCCCCSC(=S)S

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CES2 O00748 1/20 0.39
GMNN O75496 1/20 0.39
TP53 P04637 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
BLM P54132 1/20 0.39
TSHR P16473 2/20 0.38
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
CA2 P00918 3/20 0.38
ACHE P22303 2/20 0.37
MGLL Q99685 1/20 0.36
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35804 1.00 THRB (0.39) THRBHSD17B10CES2GMNNTP53
SCHEMBL20141984 1.00 THRB (0.39) THRBHSD17B10CES2GMNNTP53
SCHEMBL35364 1.00 THRB (0.39) THRBHSD17B10CES2GMNNTP53
SCHEMBL4898162 1.00 THRB (0.39) THRBHSD17B10CES2GMNNTP53
SCHEMBL30478436 1.00 THRB (0.39) THRBHSD17B10CES2GMNNTP53
SCHEMBL11441823 1.00 THRB (0.39) THRBHSD17B10CES2GMNNTP53
SCHEMBL11448250 1.00 THRB (0.39) THRBHSD17B10CES2GMNNTP53
Ammonia Solution, Strong SCHEMBL11612246 0.98 THRB (0.38) THRBHSD17B10CES2GMNNTP53
SCHEMBL9851170 0.98 THRB (0.38) THRBHSD17B10CES2GMNNTP53
SCHEMBL9788102 0.98 THRB (0.38) THRBHSD17B10CES2GMNNTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11067720-B2 Medical devices having homogeneous charge density and methods for making same JOHNSON & JOHNSON VISION CARE, INC. (US) 2021-07-20 US disclosed
US-10871595-B2 Polymers and nanogel materials and methods for making and using the same JOHNSON & JOHNSON VISION CARE, INC. (US) 2020-12-22 US disclosed
CN-111138471-A Thioacid radical end-capped mercaptosilane coupling agent and synthesis method and application thereof 怡维怡橡胶研究院有限公司 2020-05-12 CN disclosed
US-20200049858-A1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE (US) 2020-02-13 US disclosed
US-20190353829-A1 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE (US) 2019-11-21 US disclosed
EP-3141933-B9 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE (US) 2019-11-13 EP disclosed
US-10301465-B2 Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same JOHNSON & JOHNSON VISION CARE, INC. (US) 2019-05-28 US disclosed
EP-3141933-B1 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE (US) 2019-05-22 EP disclosed
US-20180341044-A1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE (US) 2018-11-29 US disclosed
EP-3401342-A1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME Johnson & Johnson Vision Care, Inc. (US) 2018-11-14 EP disclosed
EP-2566911-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME Johnson & Johnson Vision Care, Inc. (US) 2013-03-13 EP disclosed
CN-102869704-A Non-reactive, hydrophilic polymers having terminal siloxanes and uses of the same JOHNSON & JOHNSON VISION CARE 2013-01-09 CN disclosed
WO-2012151135-A1 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2012-11-08 WO disclosed
US-20120283353-A1 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE, INC. 2012-11-08 US disclosed
US-20120283353-A1 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE, INC. 2012-11-08 US disclosed
WO-2011140318-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2011-11-10 WO disclosed
US-20110275734-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. 2011-11-10 US disclosed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed
US-4215140-A Cyanomethyl alkyl trithiocarbonates as insecticidal agents ALLIED CHEMICAL CORPORATION (US) 1980-07-29 US disclosed
US-4197311-A CONTROL OF INSECTS AND ACARINA, ALSO OVICIDAL USE OF DITHIOCARBONATES AMERICAN CYANAMID COMPANY (US) 1980-04-08 US disclosed