Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169563 | 0.88 | HTR2B (0.42) | USP2HTTNCOA1NCOA3HTR2B | |
| SCHEMBL10284686 | 0.83 | JAK2 (0.41) | HTR2BHTR6KDM4ETDP1JAK2 | |
| SCHEMBL167098 | 0.82 | MEN1 (0.57) | HTR2BHTR6KIF11ALDH1A1KDM4E | |
| SCHEMBL10249379 | 0.82 | USP2 (0.52) | USP2HTTNCOA1NCOA3CYP11B1 | |
| SCHEMBL174496 | 0.81 | JAK2 (0.46) | HTR2BHTR6KIF11ALDH1A1KDM4E | |
| SCHEMBL169522 | 0.80 | ALOX5AP (0.59) | HTR2BHTR6KIF11KDM4EPIK3CA | |
| SCHEMBL175221 | 0.79 | NLRP3 (0.52) | HTTHTR2BHTR6CYP11B1CYP11B2 | |
| SCHEMBL175440 | 0.78 | S1PR1 (0.46) | CYP11B1CYP11B2KIF11AAK1S1PR1 | |
| SCHEMBL12377318 | 0.77 | CACNA1D (0.50) | ALDH1A1KDM4ETP53HSD17B10PIK3CA | |
| SCHEMBL356541 | 0.77 | JAK2 (0.52) | HTR2BHTR6CYP11B1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424856-B1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2014-12-31 | — | — | EP | disclosed |
| EP-2424856-B1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-8461181-B2 | Fused heterocyclic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2013-06-11 | — | — | US | disclosed |
| US-8461181-B2 | Fused heterocyclic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2013-06-11 | — | — | US | disclosed |
| US-8273764-B2 | Fused heterocyclic compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-25 | — | — | US | disclosed |
| US-8273764-B2 | Fused heterocyclic compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20120178779-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-07-12 | — | — | US | disclosed |
| US-20120178779-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-07-12 | — | — | US | disclosed |
| WO-2012057265-A1 | PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PESTS | 住友化学株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012057266-A1 | PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PESTS | 住友化学株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012057269-A1 | HARMFUL ANIMAL CONTROL COMPOSITION AND METHOD FOR CONTROLLING HARMFUL ANIMALS | 住友化学株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012057264-A1 | PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PESTS | 住友化学株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012057273-A1 | HARMFUL ANIMAL CONTROL COMPOSITION AND METHOD FOR CONTROLLING HARMFUL ANIMALS | 住友化学株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012057268-A1 | PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PESTS | 住友化学株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012057260-A1 | PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PESTS | 住友化学株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |
| US-20120015975-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-19 | — | — | US | disclosed |
| US-20120015975-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-19 | — | — | US | disclosed |
| WO-2010125985-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178779-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | C3AR1, C9, C5 | USP2 2313/4885HTT 582/4885NCOA1 40/4885 |
| US-20120015975-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | C3AR1, C9, C5 | USP2 2313/4885HTT 582/4885NCOA1 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.