SCHEMBL3557124

SCHEMBL3557124

CC(=O)Nc1ccc(S(=O)(=O)Nc2ccccc2CCCc2cccc(C(=O)O)c2)cc1

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 7/20 0.66
BDKRB1 P46663 6/20 0.55
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
HTT P42858 1/20 0.49
GAA P10253 1/20 0.47
GFER P55789 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3558184 0.94 SLC16A3 (0.74) SLC16A3BDKRB1MEN1KMT2AALDH1A1
SCHEMBL3563695 0.89 SLC16A3 (0.69) SLC16A3MEN1KMT2A
SCHEMBL3552582 0.89 SLC16A3 (0.59) SLC16A3BDKRB1MEN1KMT2AALDH1A1
SCHEMBL3557013 0.89 SLC16A3 (0.74) SLC16A3MEN1KMT2A
SCHEMBL3558496 0.88 SLC16A3 (0.70) SLC16A3HTT
SCHEMBL3554625 0.87 SLC16A3 (0.69) SLC16A3MEN1KMT2A
SCHEMBL3554015 0.87 SLC16A3 (0.72) SLC16A3MEN1KMT2AHTTGAA
SCHEMBL3565536 0.86 SLC16A3 (0.68) SLC16A3MEN1KMT2A
SCHEMBL3563748 0.86 SLC16A3 (0.68) SLC16A3MEN1KMT2A
SCHEMBL3559003 0.86 SLC16A3 (0.88) SLC16A3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816397-B2 Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes MERCK PATENT GMBH (DE) 2010-10-19 US claimed
US-20080045483-A1 Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes MERCK PATENT GMBH (DE) 2008-02-21 US claimed
US-7816397-B2 Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes MERCK PATENT GMBH (DE) 2010-10-19 US disclosed
US-20080045483-A1 Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes MERCK PATENT GMBH (DE) 2008-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080045483-A1 Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes SLC5A1, ALDH7A1, ASS1 SLC16A3 425/4885BDKRB1 25/4885MEN1 2548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.