SCHEMBL355778

SCHEMBL355778

O=S(=O)(O)CC(Br)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11121098 0.97 ALDH1A1 (0.39)
SCHEMBL31472783 0.97 ALDH1A1 (0.39)
SCHEMBL28662864 0.78
SCHEMBL8912263 0.78
SCHEMBL31472780 0.76
SCHEMBL27463649 0.74 SLC22A6 (0.40)
SCHEMBL27533945 0.74 TET2 (0.43)
SCHEMBL28012302 0.73
SCHEMBL11306124 0.72
SCHEMBL8897130 0.72 SLC22A6 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775173-A Method for preparing 2, 3-dibromopropane sulfonic acid 合肥立方制药股份有限公司 2025-04-08 CN claimed
CN-109651211-B Method for preparing 2, 3-dimercaptopropanesulfonic acid sodium salt 上海万巷制药有限公司 2020-11-27 CN claimed
CN-109651211-A A method of preparing 2,3- sodium dimercaptopropane sulfonate 上海万巷制药有限公司 2019-04-19 CN claimed
CN-104311466-B Synthetic method of improved sodium 2,3-dimercaptosulphonate 上海万巷制药有限公司 2017-02-01 CN claimed
CN-102531981-B A kind of mercaptolation method of improved synthetic Unithiol HEFEI LIFEON PHARMACEUTICAL CO.,LTD. (CN) 2016-05-25 CN claimed
CN-104311466-A Synthetic method of improved sodium 2,3-dimercaptosulphonate SHANGHAI WONDER PHARMACEUTICAL CO LTD 2015-01-28 CN claimed
EP-0024562-B1 PROCESS FOR THE PREPARATION OF 2,3-DIMERCAPTOPROPANE-1-SULFONIC ACID AND ITS SALTS Heyl Chemisch-pharmazeutische Fabrik GmbH &amp; Co. KG (DE) 1984-01-25 EP claimed
CN-121717743-A Preparation method of 2, 3-dimercaptopropane sodium sulfonate 合肥诺瑞特制药有限公司 2026-03-24 CN disclosed
CN-119775173-B Method for preparing 2, 3-dibromopropane sulfonic acid 合肥立方制药股份有限公司 2025-10-17 CN disclosed
CN-119775173-B Method for preparing 2, 3-dibromopropane sulfonic acid 合肥立方制药股份有限公司 2025-10-17 CN disclosed
CN-119775173-A Method for preparing 2, 3-dibromopropane sulfonic acid 合肥立方制药股份有限公司 2025-04-08 CN disclosed
CN-119775173-A Method for preparing 2, 3-dibromopropane sulfonic acid 合肥立方制药股份有限公司 2025-04-08 CN disclosed
CN-119775173-A Method for preparing 2, 3-dibromopropane sulfonic acid 合肥立方制药股份有限公司 2025-04-08 CN disclosed
EP-1836161-A2 METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES Neurochem (International) Limited (CH) 2007-09-26 EP disclosed
US-20060223855-A1 reduces or inhibits amyloid fibril formation, organ specific dysfunction (e.g., neurodegeneration), or cellular toxicity NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2006-10-05 US disclosed
WO-2006085149-A2 METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2006-08-17 WO disclosed
EP-0024562-B1 PROCESS FOR THE PREPARATION OF 2,3-DIMERCAPTOPROPANE-1-SULFONIC ACID AND ITS SALTS Heyl Chemisch-pharmazeutische Fabrik GmbH &amp; Co. KG (DE) 1984-01-25 EP disclosed
US-4382040-A REACTING ALLYL HALIDE WITH A SULFITE, BROMINATION, REACTING WITH SODIUM HYDROGEN SULFIDE, FORMING A METAL COMPLEX AND REACTING WITH HYDROGEN SULFIDE HEYL & CO. (DE) 1983-05-03 US disclosed
EP-0024562-A1 Process for the preparation of 2,3-dimercaptopropane-1-sulfonic acid and its salts Heyl Chemisch-pharmazeutische Fabrik GmbH &amp; Co. KG (DE) 1981-03-11 EP disclosed
US-3978228-A METHOD FOR KILLING NOXIOUS FUNGI IN PLANTS USING DIHALO SULFONATES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) 1976-08-31 US disclosed