SCHEMBL3558211

SCHEMBL3558211

Nc1cccc(Oc2cccc(-c3cc(Oc4cccc(N)c4)ccc3-c3ccccc3)c2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.62
ATM Q13315 1/20 0.55
GSTP1 P09211 1/20 0.46
ALDH1A1 P00352 4/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MITF O75030 1/20 0.46
GAA P10253 1/20 0.46
GFER P55789 1/20 0.46
NLRP1 Q9C000 1/20 0.46
NOD2 Q9HC29 1/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
NLRP3 Q96P20 1/20 0.45
MAOA P21397 3/20 0.44
POLB P06746 1/20 0.44
HSP90AA1 P07900 1/20 0.44
NCOA1 Q15788 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3558207 0.94 MAOB (0.68) MAOBATMGSTP1ALDH1A1MEN1
SCHEMBL8501085 0.92 MAOB (0.69) MAOBATMGSTP1ALDH1A1MEN1
SCHEMBL3557157 0.90 ALDH1A1 (0.59) MAOBATMGSTP1ALDH1A1MEN1
SCHEMBL9220634 0.88 GSTP1 (0.58) MAOBGSTP1ALDH1A1MEN1KMT2A
SCHEMBL25135231 0.85 MAOB (0.65) MAOBATMGSTP1ALDH1A1MEN1
SCHEMBL25135227 0.85 MAOB (0.65) MAOBATMGSTP1ALDH1A1MEN1
SCHEMBL25135298 0.84 MAOB (0.62) MAOBATMGSTP1ALDH1A1MEN1
SCHEMBL13445888 0.82 GSTP1 (0.52) MAOBGSTP1ALDH1A1MEN1KMT2A
SCHEMBL4326023 0.82 MAOB (0.65) MAOBATMGSTP1ALDH1A1MEN1
SCHEMBL3555602 0.81 NCOA1 (0.59) MAOBGSTP1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7820253-B2 Poly(aryletherimides) for negative birefringent films for LCDs AKRON POLYMER SYSTEMS (US) 2010-10-26 US claimed
US-20090197019-A1 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS THE UNIVERSITY OF AKRON (US) 2009-08-06 US claimed
WO-2009045537-A1 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS AKRON POLYMER SYSTEMS (US) 2009-04-09 WO claimed
JP-2009506349-A 2009-02-12 JP claimed
EP-1904603-A2 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS Akron Polymer Systems (US) 2008-04-02 EP claimed
WO-2007011911-A2 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS AKRON POLYMER SYSTEMS (US) 2007-01-25 WO claimed
US-20070014938-A1 Poly(aryletherimides) for negative birefringent films for LCDs AKRON POLYMER SYSTEMS, INC. 2007-01-18 US claimed
US-7820253-B2 Poly(aryletherimides) for negative birefringent films for LCDs AKRON POLYMER SYSTEMS (US) 2010-10-26 US disclosed
US-20090197019-A1 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS THE UNIVERSITY OF AKRON (US) 2009-08-06 US disclosed
US-20090197019-A1 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS THE UNIVERSITY OF AKRON (US) 2009-08-06 US disclosed
WO-2009045537-A1 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS AKRON POLYMER SYSTEMS (US) 2009-04-09 WO disclosed
US-7438957-B2 Poly(aryletherimides) for negative birefringent films for LCDs AKON POLYMER SYSTEMS (US) 2008-10-21 US disclosed
US-20070014938-A1 Poly(aryletherimides) for negative birefringent films for LCDs AKRON POLYMER SYSTEMS, INC. 2007-01-18 US disclosed