SCHEMBL3558358

SCHEMBL3558358

O=C(O)c1[nH]nnc1-c1ccc(O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.47
ALPL P05186 1/20 0.47
PDPK1 O15530 1/20 0.42
HSP90AB1 P08238 1/20 0.42
FGFR1 P11362 2/20 0.41
FGFR2 P21802 2/20 0.41
FGFR3 P22607 1/20 0.41
DHODH Q02127 2/20 0.39
MAP2K4 P45985 3/20 0.38
MAPK1 P28482 2/20 0.38
MAPKAPK2 P49137 2/20 0.38
MAPK6 Q16659 2/20 0.38
MAPKAPK3 Q16644 1/20 0.38
MAPKAPK5 Q8IW41 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MAPT P10636 2/20 0.38
NPC1 O15118 1/20 0.38
USP2 O75604 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23328966 0.91 MAP2K4 (0.41) CA12ALPLMAP2K4MAPK1MAPK6
SCHEMBL23294375 0.86 MAP2K4 (0.45) ALPLDHODHMAP2K4MAPK1MAPK6
SCHEMBL23294477 0.86 MAP2K4 (0.45) ALPLDHODHMAP2K4MAPK1MAPK6
SCHEMBL15946998 0.85 KDM4E (0.46) ALPLMAP2K4MAPK1MAPK6MAPKAPK3
SCHEMBL23294606 0.84 ALPL (0.49) ALPLMAP2K4MAPK1MAPKAPK2MAPK6
SCHEMBL14705874 0.84 HAO1 (0.49) CA12ALPLMAP2K4MAPK1MAPK6
SCHEMBL23294603 0.84 HAO1 (0.49) CA12ALPLMAP2K4MAPTHAO1
Hydrochloric Acid SCHEMBL3527570 0.84 KDM4E (0.44) ALPLMAP2K4MAPK1MAPK6MAPKAPK3
SCHEMBL23294326 0.83 MCL1 (0.41) DHODHMAP2K4MAPK1MAPTTP53
SCHEMBL23294600 0.83 ALPL (0.47) ALPLDHODHMAP2K4MAPK1MAPKAPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3241075-B1 STRIPPING COMPOSITIONS FOR REMOVING PHOTORESISTS FROM SEMICONDUCTOR SUBSTRATES FUJIFILM ELECTRONIC MAT USA INC (US) 2024-10-16 EP disclosed
CN-107850859-B Stripping composition for removing photoresist on semiconductor substrate 富士胶片电子材料美国有限公司 2021-06-01 CN disclosed
CN-107850859-A Stripping composition for removing photoresist on semiconductor substrate 富士胶片电子材料美国有限公司 2018-03-27 CN disclosed
US-9914902-B2 Stripping compositions for removing photoresists from semiconductor substrates FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2018-03-13 US disclosed
EP-3241075-A1 STRIPPING COMPOSITIONS FOR REMOVING PHOTORESISTS FROM SEMICONDUCTOR SUBSTRATES FujiFilm Electronic Materials USA, Inc. (US) 2017-11-08 EP disclosed
US-20160186106-A1 STRIPPING COMPOSITIONS FOR REMOVING PHOTORESISTS FROM SEMICONDUCTOR SUBSTRATES FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2016-06-30 US disclosed
CN-101203518-B Fluorene derivative, composition containing the same and use thereof AVENTIS PHARMA SA 2013-07-24 CN disclosed
US-7674795-B2 Fluorene derivatives, composition containing said derivatives and the use thereof AVENTIS PHARMA SA (FR) 2010-03-09 US disclosed
US-20080153837-A1 Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof AVENTIS PHARMA S.A. (FR) 2008-06-26 US disclosed
CN-101203518-A Novel fluorene derivatives, compositions containing same and uses thereof AVENTIS PHARMA SA (FR) 2008-06-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080153837-A1 Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof HSP90B1, HSP90AB1, HSP90AA1 CA12 4741/4885ALPL 4718/4885PDPK1 1460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.