Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3110262 | 0.92 | SLC2A1 (0.43) | SCN9ASLC2A1 | |
| SCHEMBL13439218 | 0.88 | TLR8 (0.42) | SCN9ASLC2A1MAPK14 | |
| SCHEMBL9266167 | 0.87 | SLC2A1 (0.51) | SCN9ATHRATHRBSLC2A1MAPK14 | |
| SCHEMBL3556733 | 0.83 | SLC2A1 (0.48) | SCN9ASLC2A1 | |
| SCHEMBL3561339 | 0.82 | SLC2A1 (0.40) | SLC2A1TRPC5 | |
| SCHEMBL3560834 | 0.81 | SLC2A1 (0.44) | SCN9ASLC2A1 | |
| SCHEMBL4472453 | 0.78 | SLC2A1 (0.58) | SCN9ASLC2A1 | |
| SCHEMBL13049774 | 0.78 | DGAT1 (0.40) | — | |
| SCHEMBL3711185 | 0.78 | SLC2A1 (0.38) | SLC2A1 | |
| SCHEMBL3718102 | 0.77 | SLC2A1 (0.38) | SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674808-B2 | Heterocyclic compounds | GLAXO GROUP LIMITED (GB) | 2010-03-09 | — | — | US | claimed |
| US-7674808-B2 | Heterocyclic compounds | GLAXO GROUP LIMITED (GB) | 2010-03-09 | — | — | US | disclosed |