Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 9/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 3/20 | 0.40 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555506 | 0.93 | SLC16A3 (0.60) | SLC16A3NR3C1GRIA4 | |
| SCHEMBL3553686 | 0.87 | SLC16A3 (0.58) | SLC16A3NR3C1 | |
| SCHEMBL3561531 | 0.86 | SLC16A3 (0.58) | SLC16A3PTGER1PTGER4PTGER3PTGER2 | |
| Benzene SCHEMBL3554392 | 0.86 | SLC16A3 (0.58) | SLC16A3PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3564190 | 0.85 | SLC16A3 (0.57) | SLC16A3PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3557081 | 0.82 | SLC16A3 (0.66) | SLC16A3PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3556281 | 0.82 | SLC16A3 (0.62) | SLC16A3PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3554388 | 0.81 | SLC16A3 (0.56) | SLC16A3PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3564726 | 0.81 | SLC16A3 (0.58) | SLC16A3PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3559097 | 0.81 | SLC16A3 (0.53) | SLC16A3PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | claimed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | claimed |
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | SLC16A3 425/4885PTGER1 39/4885PTGER4 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.