Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710728 | 1.00 | TSHR (1.00) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| Sulfuric Acid SCHEMBL11120128 | 0.91 | TSHR (0.83) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| Dinitrophenylene SCHEMBL27264981 | 0.89 | TSHR (0.79) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL365344 | 0.85 | TSHR (0.73) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL10918542 | 0.83 | TSHR (0.71) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL1935375 | 0.82 | TSHR (0.69) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL16744040 | 0.82 | TSHR (0.69) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| Nitrobenzene SCHEMBL11242644 | 0.82 | TSHR (0.69) | TSHRLMNAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL8713184 | 0.82 | TSHR (0.69) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL94845 | 0.82 | TSHR (0.69) | TSHRLMNAALDH1A1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1048 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478045-B | Method for synthesizing nitrobenzoic acid by one-step oxidation of nitrobenzyl chloride | 南昌大学 | 2025-02-07 | — | — | CN | claimed |
| CN-116478045-A | Method for synthesizing nitrobenzoic acid by one-step oxidation of nitrobenzyl chloride | 南昌大学 | 2023-07-25 | — | — | CN | claimed |
| CN-110540526-B | Carane acidyl 1,2, 3-triazole compound and preparation method and application thereof | 广西大学 | 2022-08-30 | — | — | CN | claimed |
| CN-114773989-A | Anti-silver colloid diffusion agent, preparation method and application thereof | 苏州瑞港环保科技有限公司 | 2022-07-22 | — | — | CN | claimed |
| US-10590145-B2 | Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent | SHANDONG UNIVERSITY (CN) | 2020-03-17 | — | — | US | claimed |
| US-20200031844-A1 | Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent | SHANDONG UNIVERSITY (CN) | 2020-01-30 | — | — | US | claimed |
| CN-110540526-A | Carane acidyl 1,2, 3-triazole compound and preparation method and application thereof | UNIV GUANGXI | 2019-12-06 | — | — | CN | claimed |
| CN-109265351-A | A kind of preparation method of the chloro- 5- nitro-toluene of 2- | 沈阳化工研究院有限公司 | 2019-01-25 | — | — | CN | claimed |
| CN-104892468-A | Preparation method of sodium 6-chloro-3-nitromethylbenzoyl-4-sulfonate | UNIV TIANJIN | 2015-09-09 | — | — | CN | claimed |
| CN-102702043-B | Method for preparing CLT acid (6-chloro-3-nitrotoluene-4-sulfonic acid) by continuous hydrogenation reduction of 6-chloro-3-nitrotoluene-4-sulfonicacid liquid phase | NINGBO INST MAT TECH & ENG CAS | 2015-04-29 | — | — | CN | claimed |
| EP-0045570-B1 | USE OF ORGANIC HALOGEN COMPOUNDS TO REDUCE OR PREVENT FOG IN NEGATIVE-WORKING SILVER HALIDE EMULSIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-09-28 | — | — | EP | claimed |
| EP-0024665-B1 | DIISOCYANATES OR MIXTURES OF DIISOCYANATES OF THE DIPHENYL-METHANE SERIES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS A SYNTHESIS COMPONENT TO PRODUCE POLYURETHANE PLASTICS ACCORDING TO THE ISOCYANATE-POLYADDITION PROCESS | BAYER AG (DE) | 1982-05-05 | — | — | EP | claimed |
| US-4323645-A | Organic halogen compounds for negative-working silver halide emulsions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-04-06 | — | — | US | claimed |
| EP-0046917-A1 | Polyisocyanate mixtures of the diphenylmethane class, as well as their use as synthesis components in the manufacture of polyurethanes by the isocyanate-polyaddition process | BAYER AG (DE) | 1982-03-10 | — | — | EP | claimed |
| EP-0045570-A1 | Use of organic halogen compounds to reduce or prevent fog in negative-working silver halide emulsions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-02-10 | — | — | EP | claimed |
| EP-0016061-A4 | ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS. | DU PONT (US) | 1981-08-27 | — | — | EP | claimed |
| US-4257915-A | USE IN PHOTOPOLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | claimed |
| EP-0024665-A1 | Diisocyanates or mixtures of diisocyanates of the diphenyl-methane series, process for their preparation and their use as a synthesis component to produce polyurethane plastics according to the isocyanate-polyaddition process | BAYER AG (DE) | 1981-03-11 | — | — | EP | claimed |
| EP-0016061-A1 | ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS. | DU PONT (US) | 1980-10-01 | — | — | EP | claimed |
| WO-1980000040-A1 | ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS | DU PONT (US) | 1980-01-10 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10590145-B2 | Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent | TYMP, DPYD, TPMT | TSHR 4771/4885LMNA 4779/4885ALDH1A1 931/4885 |
| US-20200031844-A1 | Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent | TYMP, DPYD, TPMT | TSHR 4771/4885LMNA 4779/4885ALDH1A1 931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.