Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365344 | 0.89 | TSHR (0.73) | TSHRSIGMAR1LMNAALDH1A1TDP1 | |
| SCHEMBL8867687 | 0.84 | TSHR (0.61) | TSHRSIGMAR1LMNAALDH1A1TDP1 | |
| SCHEMBL81981 | 0.83 | TSHR (0.59) | TSHRSIGMAR1LMNAALDH1A1TDP1 | |
| SCHEMBL9172279 | 0.83 | TSHR (0.59) | TSHRSIGMAR1LMNAALDH1A1TDP1 | |
| SCHEMBL81026 | 0.83 | TSHR (0.59) | TSHRSIGMAR1LMNAALDH1A1MEN1 | |
| SCHEMBL7328646 | 0.83 | TSHR (0.59) | TSHRSIGMAR1LMNAALDH1A1TDP1 | |
| SCHEMBL6998770 | 0.83 | TSHR (0.59) | TSHRSIGMAR1LMNAALDH1A1TDP1 | |
| SCHEMBL9172285 | 0.83 | TSHR (0.59) | TSHRSIGMAR1LMNAALDH1A1MEN1 | |
| SCHEMBL356063 | 0.82 | TSHR (1.00) | TSHRLMNAALDH1A1TDP1MEN1 | |
| SCHEMBL9710728 | 0.82 | TSHR (1.00) | TSHRLMNAALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331512-A1 | ALKOXY-SUBSTITUTED AND ALKYLTHIO-SUBSTITUTED ANILINOPYRIMIDINES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025833-A1 | ALKOXY-SUBSTITUTED AND ALKYLTHIO-SUBSTITUTED ANILINOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |