Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.53 |
| ▸ | CCKAR | P32238 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | GHSR | Q92847 | 1/20 | 0.53 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.53 |
| ▸ | CTSD | P07339 | 4/20 | 0.48 |
| ▸ | CTSE | P14091 | 1/20 | 0.48 |
| ▸ | PGC | P20142 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 8/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 8/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 8/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 8/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3560633 | 1.00 | MLNR (0.53) | MLNRNR1I2SLCO2B1ABCB11ABCB1 | |
| SCHEMBL3545341 | 0.95 | UGT1A1 (0.51) | MLNRNR1I2SLCO2B1ABCB11ABCB1 | |
| SCHEMBL3554832 | 0.95 | MLNR (0.51) | MLNRNR1I2SLCO2B1ABCB11ABCB1 | |
| SCHEMBL3545339 | 0.95 | UGT1A1 (0.51) | MLNRNR1I2SLCO2B1ABCB11ABCB1 | |
| SCHEMBL3554834 | 0.95 | MLNR (0.51) | MLNRNR1I2SLCO2B1ABCB11ABCB1 | |
| SCHEMBL3552162 | 0.90 | UGT1A1 (0.70) | MLNRNR1I2SLCO2B1ABCB11ABCB1 | |
| SCHEMBL3552166 | 0.90 | UGT1A1 (0.70) | MLNRNR1I2SLCO2B1ABCB11ABCB1 | |
| SCHEMBL7484979 | 0.87 | MLNR (0.52) | MLNRNR1I2SLCO2B1ABCB11ABCB1 | |
| SCHEMBL7483928 | 0.87 | MLNR (0.52) | MLNRNR1I2SLCO2B1ABCB11ABCB1 | |
| SCHEMBL7484988 | 0.87 | MLNR (0.52) | MLNRNR1I2SLCO2B1ABCB11ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697348-B1 | HIV PROTEASE INHIBITING COMPOUNDS | ABBOTT LAB (US) | 2011-12-28 | — | — | EP | disclosed |
| US-7696226-B2 | HIV protease inhibiting compounds | ABBOTT LABORATORIES (US) | 2010-04-13 | — | — | US | disclosed |
| US-20050159469-A1 | HIV protease inhibiting compounds | ABBVIE INC. | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159469-A1 | HIV protease inhibiting compounds | SERPINB1, HPN, DNPEP | MLNR 3723/4885NR1I2 3691/4885SLCO2B1 3853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.