SCHEMBL356240

SCHEMBL356240

BNc1cccc([N+](=O)[O-])c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.62
MEN1 O00255 3/20 0.62
POLB P06746 2/20 0.62
MAPT P10636 2/20 0.62
DDX3X O00571 1/20 0.62
HTT P42858 1/20 0.62
CTDSP1 Q9GZU7 1/20 0.62
TSHR P16473 3/20 0.61
LMNA P02545 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.59
BLM P54132 1/20 0.56
ALDH1A1 P00352 6/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
MMP2 P08253 1/20 0.54
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
ACHE P22303 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394734 0.83 KMT2A (0.67) KMT2AMEN1POLBMAPTDDX3X
SCHEMBL775954 0.82 KMT2A (0.65) KMT2AMEN1POLBMAPTDDX3X
SCHEMBL27695100 0.80 KMT2A (0.62) KMT2AMEN1POLBMAPTDDX3X
SCHEMBL27866569 0.80 KMT2A (0.62) KMT2AMEN1POLBMAPTDDX3X
SCHEMBL11445187 0.80 MAPT (0.68) KMT2AMEN1POLBMAPTDDX3X
SCHEMBL1143356 0.80 KMT2A (0.62) KMT2AMEN1POLBMAPTDDX3X
SCHEMBL4271088 0.80 KMT2A (0.62) KMT2AMEN1POLBMAPTDDX3X
SCHEMBL9382265 0.80 KMT2A (0.62) KMT2AMEN1POLBMAPTDDX3X
SCHEMBL732435 0.80 SMN1; SMN2 (0.64) KMT2AMEN1POLBMAPTDDX3X
SCHEMBL12728640 0.79 MEN1 (0.81) KMT2AMEN1POLBMAPTDDX3X

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8637703-B2 Methods for synthesizing ammonia borane THE OHIO STATE UNIVERSITY (US) 2014-01-28 US claimed
US-8637703-B2 Methods for synthesizing ammonia borane THE OHIO STATE UNIVERSITY (US) 2014-01-28 US disclosed
EP-2007743-B1 METHODS FOR SYNTHESIZING AMMONIA BORANE UNIV OHIO STATE (US) 2013-06-12 EP disclosed
US-20120014857-A1 METHODS FOR SYNTHESIZING AMMONIA BORANE THE OHIO STATE UNIVERSITY (US) 2012-01-19 US disclosed
US-7977508-B2 Methods for synthesizing ammonia borane THE OHIO STATE UNIVERSITY (US) 2011-07-12 US disclosed
US-20090104102-A1 METHODS FOR SYNTHESIZING AMMONIA BORANE THE OHIO STATE UNIVERSITY 2009-04-23 US disclosed
EP-2007743-A2 METHODS FOR SYNTHESIZING AMMONIA BORANE The Ohio State University (US) 2008-12-31 EP disclosed
WO-2007120511-A2 METHODS FOR SYNTHESIZING AMMONIA BORANE THE OHIO STATE UNIVERSITY (US) 2007-10-25 WO disclosed