Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | DDX3X | O00571 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122195 | 0.86 | KMT2A (0.59) | KMT2AMEN1POLBMAPTDDX3X | |
| SCHEMBL394734 | 0.85 | KMT2A (0.67) | KMT2AMEN1POLBMAPTDDX3X | |
| Hydrochloric Acid SCHEMBL9594727 | 0.85 | KMT2A (0.57) | KMT2AMEN1POLBMAPTDDX3X | |
| SCHEMBL11775765 | 0.82 | SMN1; SMN2 (0.60) | KMT2AMEN1POLBMAPTDDX3X | |
| SCHEMBL356240 | 0.82 | KMT2A (0.62) | KMT2AMEN1POLBMAPTDDX3X | |
| SCHEMBL4271088 | 0.82 | KMT2A (0.62) | KMT2AMEN1POLBMAPTDDX3X | |
| SCHEMBL9382265 | 0.82 | KMT2A (0.62) | KMT2AMEN1POLBMAPTDDX3X | |
| SCHEMBL1143356 | 0.82 | KMT2A (0.62) | KMT2AMEN1POLBMAPTDDX3X | |
| SCHEMBL732435 | 0.82 | SMN1; SMN2 (0.64) | KMT2AMEN1POLBMAPTDDX3X | |
| SCHEMBL27866569 | 0.82 | KMT2A (0.62) | KMT2AMEN1POLBMAPTDDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646234-A | 2-bromo-5-nitrophenylamine and preparation method thereof | 叶芳 | 2016-06-08 | — | — | CN | claimed |
| CN-110483366-A | Benzazole compounds and preparation method thereof, pharmaceutical composition and purposes | INST MATERIA MEDICA CAMS | 2019-11-22 | — | — | CN | disclosed |
| CN-110325532-A | Aryl hydrocarbon receptor (AhR) adjusts immunomodulator compounds | 菲尼克斯药品股份公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-110256258-A | A method of photocatalytic synthesis is at more bromoaniline compounds in water phase | 福建医科大学 | 2019-09-20 | — | — | CN | disclosed |
| CN-110195237-A | A method of using bromide as bromating agent, the electro-catalysis in water phase prepares more bromoaniline compounds | 福建医科大学 | 2019-09-03 | — | — | CN | disclosed |
| CN-105814040-B | The condensed 1,4- dihydro two of inhibitor as thermal excited transcryption factor 1 dislikes ene derivative | 癌症研究科技有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-110003171-A | The small molecule invertibity BTK inhibitor for treating rheumatoid arthritis | 清华大学 | 2019-07-12 | — | — | CN | disclosed |
| CN-106132962-B | Macrocyclic compounds having an aromatic P2' group as factor XIA inhibitors | 百时美施贵宝公司 | 2018-09-07 | — | — | CN | disclosed |
| CN-108430471-A | Factor xia inhibitors | 默沙东公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-108250199-A | Dihydropyridone P1 is as factor XIA inhibitors | 百时美施贵宝公司 | 2018-07-06 | — | — | CN | disclosed |
| EP-2509954-A1 | 4 -OXO- 1H -QUINOLINE- 3 - CARBOXAMIDES AS MODULATORS OF ATP -BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2012-10-17 | — | — | EP | disclosed |
| US-20120071488-A1 | MELTING TABLET CONTAINING A SILDENAFIL SALT | RATIOPHARM GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
| CN-102170882-A | Compositions and methods of treating amyloid disease | TREVENTIS CORP | 2011-08-31 | — | — | CN | disclosed |
| WO-2011076411-A1 | ORODISPERSIBLE TABLET CONTAINED COMPACTED SILDENAFIL BASE | RATIOPHARM GMBH (DE) | 2011-06-30 | — | — | WO | disclosed |
| WO-2011072839-A1 | ORODISPERSIBLE TABLET, CONTAINING DAPOXETINE | RATIOPHARM GMBH (DE) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011072241-A1 | 4 -OXO- IH -QUINOLINE- 3 - CARBOXAMIDES AS MODULATORS OF ATP -BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-06-16 | — | — | WO | disclosed |
| CN-102015651-A | Compounds and compositions as TLR activity modulators | IRM LLC | 2011-04-13 | — | — | CN | disclosed |
| CN-101935301-A | Modulators of ATP-binding cassette transporters | VERTEX PHARMA | 2011-01-05 | — | — | CN | disclosed |
| CN-101891680-A | The adjusting control agent of ATP- combination cassette transporters | VERTEX PHARMA | 2010-11-24 | — | — | CN | disclosed |
| CN-1021010-C | SUBSTITUTED THIAZOLES COMPOSITION AND THEIR USE AS FUNGICIDES | MONSANTO CO (US) | 1993-06-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071488-A1 | MELTING TABLET CONTAINING A SILDENAFIL SALT | PDE9A, SORD, TAS2R39 | KMT2A 2231/4885MEN1 1511/4885POLB 2919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.