Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3563589 | 0.92 | MAPT (0.55) | MAPTALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL261551 | 0.85 | NOTUM (0.52) | MAPTNOTUMALDH1A1KMT2AKDM4E | |
| SCHEMBL15758318 | 0.82 | NOTUM (0.56) | NOTUMALDH1A1KMT2AKDM4EHPGD | |
| SCHEMBL69740 | 0.80 | NR4A2 (0.48) | MAPTALDH1A1KDM4EGLAGAA | |
| SCHEMBL11933614 | 0.78 | MAPT (0.43) | MAPTALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL9148730 | 0.74 | MAPT (0.43) | MAPTALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL30819290 | 0.73 | KDM4E (0.46) | MAPTALDH1A1KDM4EHPGDNR4A2 | |
| SCHEMBL29772061 | 0.72 | NOTUM (0.71) | NOTUMALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL1155989 | 0.72 | NOTUM (0.58) | MAPTNOTUMALDH1A1KMT2AKDM4E | |
| SCHEMBL4308193 | 0.72 | CYP1A2 (0.50) | MAPTALDH1A1KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793254-B | Azaquinazoline carboxamide derivatives | 默克专利有限公司 | 2020-10-23 | — | — | CN | disclosed |
| US-7659307-B2 | Nonphytotoxic; 4-Bromo-3-methoxy-N-4-[4(trifluoromethyl)phenoxy]phenyl-thiophene-2-carboxamide; 4-[(Allyloxycarbonyl)amino]-3-methoxy-N-4-[4-(trifluoromethyl)phenoxy]phenyl-thiophene-2-carboxamide | BAYER CROPSCIENCE S.A. (FR) | 2010-02-09 | — | — | US | disclosed |
| US-20060205732-A1 | Heterocyclic carboxamides and their use as fungicides | BAYER SAS (FR) | 2006-09-14 | — | — | US | disclosed |
| US-7084163-B2 | Heterocyclic carboxamides and their use as fungicides | BAYER CROPSCIENCE S.A. (FR) | 2006-08-01 | — | — | US | disclosed |
| US-20040152698-A1 | Heterocyclic carboxamides and their use as fungicides | BAYER SAS (FR) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152698-A1 | Heterocyclic carboxamides and their use as fungicides | CYP1A2, CYP4X1, CYCS | MAPT 4778/4885NOTUM 733/4885ALDH1A1 3137/4885 |
| US-20060205732-A1 | Heterocyclic carboxamides and their use as fungicides | CYP4X1, CYP1A2, CYCS | MAPT 4693/4885NOTUM 791/4885ALDH1A1 2827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.