SCHEMBL356397

SCHEMBL356397

C=C(C)C(=O)OCCNC(C)CCC=CC=CCC

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL353384 0.83 TSHR (0.40) TSHRTHRB
SCHEMBL9635967 0.82 TSHR (0.49) TSHRTHRB
SCHEMBL29107017 0.79 TSHR (0.54) TSHRTHRB
SCHEMBL3281742 0.78 THRB (0.49) TSHRTHRB
SCHEMBL356388 0.77 TSHR (0.44) TSHRTHRB
SCHEMBL355560 0.74 TSHR (0.41) TSHRTHRB
SCHEMBL345374 0.73 TSHR (0.52) TSHRTHRB
SCHEMBL354079 0.73 THRB (0.59) TSHRTHRB
SCHEMBL354080 0.73 THRB (0.59) TSHRTHRB
SCHEMBL355084 0.72 TSHR (0.45) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420709-B2 Coating composition, (meth)acrylic polymer and monomer mixture for producing the (meth)acrylic polymer EVONIK RÖHM GMBH (DE) 2013-04-16 US disclosed
US-8415422-B2 (Meth)acrylate monomer, polymer and coating agent EVONIK RÖHM GMBH (DE) 2013-04-09 US disclosed
US-20120065322-A1 (METH)ACRYLATE POLYMER, COATING AGENT, METHOD FOR PRODUCING A COATING, AND COATED OBJECT EVONIK ROEHM GMBH (DE) 2012-03-15 US disclosed
US-20120016071-A1 POLYFUNCTIONAL (METH)ACRYLIC POLYMER, COATING COMPOSITION, PROCESS FOR PRODUCING A COATING AND COATED ARTICLE EVONIK ROEHM GMBH (DE) 2012-01-19 US disclosed
US-20110318595-A1 COATING COMPOSITION, (METH)ACRYLIC POLYMER AND MONOMER MIXTURE FOR PRODUCING THE (METH)ACRYLIC POLYMER EVONIK ROEHM GMBH (DE) 2011-12-29 US disclosed
US-20110144267-A1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD EVONIK ROEHM GMBH (DE) 2011-06-16 US disclosed
US-20110130509-A1 (METH)ACRYLATE MONOMER, POLYMER AND COATING AGENT EVONIK ROEHM GMBH (DE) 2011-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144267-A1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD DNMT1, TET1, MGMT TSHR 2023/4885THRB 2750/4885
US-20110130509-A1 (METH)ACRYLATE MONOMER, POLYMER AND COATING AGENT MGMT, DNMT1, TET1 TSHR 1058/4885THRB 1927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.