SCHEMBL35651

SCHEMBL35651

CCCCNC(=NC1CCCCC1)NC1CCCCC1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.56
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
EPHX1 P07099 12/20 0.53
EPHX2 P34913 2/20 0.51
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35650 1.00 SIGMAR1 (0.56) SIGMAR1MEN1KMT2AEPHX1EPHX2
SCHEMBL12236605 1.00 SIGMAR1 (0.56) SIGMAR1MEN1KMT2AEPHX1EPHX2
SCHEMBL19286042 0.95 EPHX1 (0.59) SIGMAR1MEN1KMT2AEPHX1EPHX2
SCHEMBL16661526 0.95 EPHX1 (0.59) SIGMAR1MEN1KMT2AEPHX1EPHX2
SCHEMBL17187474 0.94 EPHX1 (0.60) SIGMAR1MEN1KMT2AEPHX1EPHX2
SCHEMBL17187505 0.94 EPHX1 (0.60) SIGMAR1MEN1KMT2AEPHX1EPHX2
SCHEMBL9543418 0.94 EPHX1 (0.60) SIGMAR1MEN1KMT2AEPHX1EPHX2
SCHEMBL17187473 0.94 EPHX1 (0.60) SIGMAR1MEN1KMT2AEPHX1EPHX2
SCHEMBL18428870 0.94 EPHX1 (0.60) SIGMAR1MEN1KMT2AEPHX1EPHX2
SCHEMBL17187465 0.94 EPHX1 (0.60) SIGMAR1MEN1KMT2AEPHX1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9102780-B2 Catalysts for reaction between an isocyanate and an alcohol BLUESTAR SILICONES FRANCE SAS (FR) 2015-08-11 US claimed
EP-3699224-A1 SCORCH RETARDANT HALOGENATED FLAME RETARDANT COMPOUNDS AND ARTICLES MADE THEREFROM PolyOne Corporation (US) 2020-08-26 EP disclosed
EP-2370488-B1 NOVEL CATALYSTS FOR REACTION BETWEEN AN ISOCYANATE AND AN ALCOHOL ELKEM SILICONES FRANCE SAS (FR) 2020-03-25 EP disclosed
CN-106432772-A Silicone composition which is cross-linkable by dehydrogenative condensation in the presence of a non-metal catalyst 蓝星有机硅法国公司 2017-02-22 CN disclosed
EP-2556116-B1 METHOD AND COMPOSITIONS FOR THE SEALING AND ASSEMBLY OF POWER TRAIN COMPONENTS BLUESTAR SILICONES FRANCE (FR) 2016-08-17 EP disclosed
US-9102780-B2 Catalysts for reaction between an isocyanate and an alcohol BLUESTAR SILICONES FRANCE SAS (FR) 2015-08-11 US disclosed
EP-2268743-B1 COMPOUNDS HAVING A GUANIDINE STRUCTURE AND USE OF SAME AS ORGANOPOLYSILOXANE POLYCONDENSATION CATALYSTS BLUESTAR SILICONES FRANCE (FR) 2015-04-22 EP disclosed
CN-102803414-B Method for coating a tin-free silicon composition on a flexible medium BLUESTAR SILICONES FRANCE 2015-04-22 CN disclosed
CN-102884136-B Methods and compositions for sealing and assembling engine block components BLUESTAR SILICONES FRANCE (FR) 2014-10-01 CN disclosed
US-8841372-B2 Method and compositions for the sealing and assembly of power train components BLUESTAR SILICONES FRANCE SAS (FR) 2014-09-23 US disclosed
WO-2011114021-A1 METHOD AND COMPOSITIONS FOR THE SEALING AND ASSEMBLY OF POWER TRAIN COMPONENTS BLUESTAR SILICONES FRANCE (FR) 2011-09-22 WO disclosed
CN-102083912-A Compound with guanidine structure and application thereof as organopolysiloxane polycondensation catalyst BLUESTAR SILICONES FRANCE 2011-06-01 CN disclosed
CN-102056996-A Article having antisoiling properties and intended to be employed in aquatic uses, in particular marine uses BLUESTAR SILICONES FRANCE 2011-05-11 CN disclosed
US-20110098392-A1 COMPOUNDS HAVING A GUANIDINE STRUCTURE AND USE OF SAME AS ORGANOPOLYSILOXANE POLYCONDENSATION CATALYSTS BLUESTAR SILICONES FRANCE (FR) 2011-04-28 US disclosed
EP-2291462-A1 ARTICLE HAVING ANTISOILING PROPERTIES AND INTENDED TO BE EMPLOYED IN AQUATIC USES, IN PARTICULAR MARINE USES Bluestar Silicones France (FR) 2011-03-09 EP disclosed
EP-2268743-A2 COMPOUNDS HAVING A GUANIDINE STRUCTURE AND USE OF SAME AS ORGANOPOLYSILOXANE POLYCONDENSATION CATALYSTS Bluestar Silicones France (FR) 2011-01-05 EP disclosed
WO-2010146249-A1 METHOD FOR COATING A TIN-FREE SILICON COMPOSITION ON A FLEXIBLE MEDIUM BLUESTAR SILICONES FRANCE (FR) 2010-12-23 WO disclosed
WO-2010146252-A2 COMPOSITION FOR WATERPROOFING AND IMPROVING THE BEADING EFFECT OF CONSTRUCTION MATERIALS BLUESTAR SILICONES FRANCE (FR) 2010-12-23 WO disclosed
WO-2009133084-A1 ARTICLE HAVING ANTISOILING PROPERTIES AND INTENDED TO BE EMPLOYED IN AQUATIC USES, IN PARTICULAR MARINE USES BLUESTAR SILICONES FRANCE (FR) 2009-11-05 WO disclosed
WO-2009118307-A2 COMPOUNDS HAVING A GUANIDINE STRUCTURE AND USE OF SAME AS ORGANOPOLYSILOXANE POLYCONDENSATION CATALYSTS BLUESTAR SILICONES FRANCE (FR) 2009-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098392-A1 COMPOUNDS HAVING A GUANIDINE STRUCTURE AND USE OF SAME AS ORGANOPOLYSILOXANE POLYCONDENSATION CATALYSTS GMNN, GLMN, IDUA SIGMAR1 1235/4885MEN1 2245/4885KMT2A 971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.