Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 0.78 |
| ▸ | HTR2A | P28223 | 15/20 | 0.78 |
| ▸ | HTR6 | P50406 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3571313 | 0.88 | SLC6A2 (0.81) | SLC6A2HTR2AHTR6HTR2CHTR1A | |
| SCHEMBL3572919 | 0.87 | HTR2A (1.00) | SLC6A2HTR2AHTR6HTR2CHTR1A | |
| SCHEMBL3569587 | 0.87 | HTR2A (0.80) | SLC6A2HTR2AHTR6HTR2CHTR1A | |
| SCHEMBL3566291 | 0.86 | HTR2A (1.00) | SLC6A2HTR2AHTR6HTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL3570714 | 0.85 | HTR2A (0.98) | SLC6A2HTR2AHTR6HTR2CHTR1A | |
| SCHEMBL3569544 | 0.83 | SLC6A2 (1.00) | SLC6A2HTR2AHTR6HTR2C | |
| SCHEMBL3571043 | 0.81 | SLC6A2 (1.00) | SLC6A2HTR2AHTR6HTR2CPTGER3 | |
| SCHEMBL3566194 | 0.80 | HTR2A (1.00) | SLC6A2HTR2AHTR6HTR2CHTR1A | |
| SCHEMBL3569288 | 0.79 | SLC6A2 (0.76) | SLC6A2HTR2AHTR6HTR2CPTGER3 | |
| SCHEMBL3565077 | 0.79 | SLC6A2 (1.00) | SLC6A2HTR2AHTR6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645752-B2 | Sulfonyl substituted 1H-indoles as ligands for the 5-hydroxytryptamine receptors | WYETH LLC (US) | 2010-01-12 | — | — | US | claimed |
| EP-1973876-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | Wyeth (US) | 2008-10-01 | — | — | EP | claimed |
| US-20070203120-A1 | Sulfonyl Substituted 1H-Indoles as Ligands for the 5-Hydroxytryptamine Receptors | WYETH (US) | 2007-08-30 | — | — | US | claimed |
| WO-2007084841-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | WYETH (US) | 2007-07-26 | — | — | WO | claimed |
| US-7645752-B2 | Sulfonyl substituted 1H-indoles as ligands for the 5-hydroxytryptamine receptors | WYETH LLC (US) | 2010-01-12 | — | — | US | disclosed |
| EP-1973876-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | Wyeth (US) | 2008-10-01 | — | — | EP | disclosed |
| US-20070203120-A1 | Sulfonyl Substituted 1H-Indoles as Ligands for the 5-Hydroxytryptamine Receptors | WYETH (US) | 2007-08-30 | — | — | US | disclosed |
| WO-2007084841-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | WYETH (US) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203120-A1 | Sulfonyl Substituted 1H-Indoles as Ligands for the 5-Hydroxytryptamine Receptors | HTR5A, HTR2C, HTR2A | SLC6A2 20/4885HTR2A 3/4885HTR6 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.