⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12848309 | 0.75 | — | — | |
| SCHEMBL24299509 | 0.67 | — | — | |
| SCHEMBL2102273 | 0.67 | — | — | |
| SCHEMBL25967494 | 0.67 | — | — | |
| SCHEMBL1338815 | 0.67 | — | — | |
| SCHEMBL9587525 | 0.66 | MAPK1 (0.31) | — | |
| SCHEMBL6450406 | 0.65 | TSHR (0.33) | — | |
| SCHEMBL627752 | 0.65 | — | — | |
| SCHEMBL22760457 | 0.65 | — | — | |
| SCHEMBL7931709 | 0.65 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115573055-A | Antimony-free low-melting-point polyester fiber and preparation method thereof | 四川汇维仕化纤有限公司 | 2023-01-06 | — | — | CN | claimed |
| CN-109180578-B | Preparation method of bosutinib | 山东创新药物研发有限公司 | 2020-06-26 | — | — | CN | claimed |
| US-11866520-B2 | Functionalised compounds | PHOSPHONICS LIMITED (GB) | 2024-01-09 | — | — | US | disclosed |
| US-20230382856-A1 | METHOD OF PRODUCING 3-METHYL-4-HALO-INDOLE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-11-30 | — | — | US | disclosed |
| EP-4238961-A1 | METHOD OF PRODUCING 3-METHYL-4-HALO-INDOLE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2023-09-06 | — | — | EP | disclosed |
| CN-116368125-A | Process for producing 3-methyl-4-halogeno-indole derivative | 第一三共株式会社 | 2023-06-30 | — | — | CN | disclosed |
| EP-3713968-B1 | FUNCTIONALISED COMPOUNDS | PHOSPHONICS LTD (GB) | 2023-03-29 | — | — | EP | disclosed |
| WO-2022092247-A1 | METHOD OF PRODUCING 3-METHYL-4-HALO-INDOLE DERIVATIVE | 第一三共株式会社 | 2022-05-05 | — | — | WO | disclosed |
| US-20210147578-A1 | Functionalised Compounds | PHOSPHONICS LIMITED (GB) | 2021-05-20 | — | — | US | disclosed |
| EP-3713968-A1 | FUNCTIONALISED COMPOUNDS | Phosphonics Limited (GB) | 2020-09-30 | — | — | EP | disclosed |
| CN-111511774-A | Functionalized compounds | 磷化有限公司 | 2020-08-07 | — | — | CN | disclosed |
| US-9365582-B2 | Macrocyclic inhibitors of hepatitis C virus | JANSSEN SCIENCES IRELAND UC (IE) | 2016-06-14 | — | — | US | disclosed |
| CN-105377286-A | CONOTOXIN (CONOTOXIN) peptides, pharmaceutical compositions and uses thereof | UNIV UTAH RES FOUND | 2016-03-02 | — | — | CN | disclosed |
| CN-101535294-B | Macrocyclic inhibitors of hepatitis c virus | TIBOTEC PHARM LTD | 2014-09-24 | — | — | CN | disclosed |
| US-20140113929-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS | Janssen R&D Ireland (formerly Tibotec Pharmaceuticals) (IE) | 2014-04-24 | — | — | US | disclosed |
| US-8637663-B2 | Macrocyclic inhibitors of hepatitis C virus | JANSSEN R&D IRELAND (IE) | 2014-01-28 | — | — | US | disclosed |
| US-20100022578-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS | JANSSEN SCIENCES IRELAND UC (IE) | 2010-01-28 | — | — | US | disclosed |
| CN-101535294-A | Macrocyclic inhibitors of hepatitis C virus | TIBOTEC PHARM LTD (IE) | 2009-09-16 | — | — | CN | disclosed |
| EP-2097402-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS | Tibotec Pharmaceuticals Ltd. (IE) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008059046-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-05-22 | — | — | WO | disclosed |